Jane Huang - 04 Oct 2025 Form 4 Insider Report for Prelude Therapeutics Inc (PRLD)

Reporting relationship: President, CMO
Issuer ticker: PRLD
Reported as of: 04 Oct 2025
Net transaction value: -$4,932
SEC form: 4
Accepted by SEC: 07 Oct 2025, 07:05:37 UTC
Prior SEC filing: 08 Jul 2025
Next SEC filing: 16 Jun 2026
Source filing: View source filing
Reporting owner signature: /s/ Bryant D. Lim, Attorney-in-Fact

Key filing fact

Jane Huang filed Form 4 for Prelude Therapeutics Inc (PRLD) on 07 Oct 2025.

Key facts

This page summarizes Jane Huang's Form 4 filing for Prelude Therapeutics Inc (PRLD).
3 reported transactions and 1 derivative row are listed below.
Accepted by SEC: 07 Oct 2025, 07:05.

Change

Previous filing in this sequence was filed on 08 Jul 2025.
Current net transaction value: -$4,932.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001683913 Primary reporting owner

Huang Jane

Relationship: President, CMO
Address: C/O PRELUDE THERAPEUTICS INCORPORATED, 175 INNOVATION BOULEVARD, WILMINGTON
Signature: /s/ Bryant D. Lim, Attorney-in-Fact
Signature date: 07 Oct 2025

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

PRLD transaction

Common Stock

Options Exercise

Transaction value
Shares: +9,375
Change %: +12%
Price
Shares after: 90,272
Date: 04 Oct 2025
Ownership: Direct
Footnotes: F1

PRLD transaction

Common Stock

Tax liability

Transaction value: $4,932
Shares: -3,355
Change %: -3.7%
Price: $1.47
Shares after: 86,917
Date: 04 Oct 2025
Ownership: Direct
Footnotes: F2

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

PRLD transaction Derivative

Restricted Stock Unit

Options Exercise

Transaction value: $0
Shares: -9,375
Change %: -33%
Price: $0.000000
Shares after: 18,750
Date: 04 Oct 2025
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 9,375
Exercise price
Footnotes: F1, F3

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 3 footnotes

Footnote F1

Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of Issuer's Common Stock.

Footnote F2

Represents shares withheld by the Issuer to satisfy the tax withholding obligation in connection with the vesting of RSUs.

Footnote F3

The RSUs were granted on May 2, 2022 and vest according to the reporting person's employment agreement. The RSUs vested as to 1/4 of the total shares on April 4, 2023, and 1/16 of the remaining shares shall vest quarterly thereafter until fully vested, subject to the continued service of the Reporting Person to the Issuer through each vesting date.