GV 2021 GP, L.L.C. - 01 Aug 2025 Form 4 Insider Report for Prime Medicine, Inc. (PRME)

Reporting relationship: 10%+ Owner
Issuer ticker: PRME
Reported as of: 01 Aug 2025
Net transaction value: +$4,950,000
SEC form: 4
Accepted by SEC: 05 Aug 2025, 16:07:52 UTC
Prior SEC filing: 09 May 2023
Source filing: View source filing
Reporting owner signature: /s/ Inga Goldbard, General Counsel of GV 2021 GP, L.L.C.

Key filing fact

GV 2021 GP, L.L.C. filed Form 4 for Prime Medicine, Inc. (PRME) on 05 Aug 2025.

Key facts

This page summarizes GV 2021 GP, L.L.C.'s Form 4 filing for Prime Medicine, Inc. (PRME).
1 reported transaction and 0 derivative rows are listed below.
Accepted by SEC: 05 Aug 2025, 16:07.

Change

Previous filing in this sequence was filed on 09 May 2023.
Current net transaction value: +$4,950,000.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (4)

CIK 0001861206 Primary reporting owner

GV 2021 GP, L.L.C.

Relationship: 10%+ Owner
Address: 1600 AMPHITHEATRE PARKWAY, MOUNTAIN VIEW
Signature: /s/ Inga Goldbard, General Counsel of GV 2021 GP, L.L.C.
Signature date: 05 Aug 2025

CIK 0001861216

GV 2021 GP, L.P.

Relationship: 10%+ Owner
Address: 1600 AMPHITHEATRE PARKWAY, MOUNTAIN VIEW
Signature: /s/ Inga Goldbard, General Counsel of GV 2021 GP, L.P.
Signature date: 05 Aug 2025

CIK 0001861202

GV 2021, L.P.

Relationship: 10%+ Owner
Address: 1600 AMPHITHEATRE PARKWAY, MOUNTAIN VIEW
Signature: /s/ Inga Goldbard, General Counsel of GV 2021, L.P.
Signature date: 05 Aug 2025

CIK 0001652044

Alphabet Inc.

Relationship: 10%+ Owner
Address: 1600 AMPHITHEATRE PARKWAY, MOUNTAIN VIEW
Signature: /s/ Kathryn W. Hall, Assistant Secretary of Alphabet Inc.
Signature date: 05 Aug 2025

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

PRME transaction

Common Stock

Purchase

Transaction value: $4,950,000
Shares: +1,500,000
Change %: +85%
Price: $3.30
Shares after: 3,262,440
Date: 01 Aug 2025
Ownership: By GV 2021, L.P.
Footnotes: F1, F2

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 2 footnotes

Footnote F1

Represents shares purchased in connection with an underwritten public offering of the Issuer's Common Stock that closed on August 1, 2025.

Footnote F2

The securities reported in this row are directly beneficially owned by GV 2021, L.P. (the "2021 Partnership"). The general partner of the 2021 Partnership is GV 2021 GP, L.P. (the "2021 GP"). The general partner of the 2021 GP is GV 2021 GP, L.L.C. ("GV 2021 LLC"). The sole member of GV 2021 LLC is Alphabet Holdings LLC ("Alphabet Holdings"). The sole member of Alphabet Holdings is XXVI Holdings Inc. ("XXVI"). The controlling stockholder of XXVI is Alphabet Inc. Each of the 2021 GP, GV 2021 LLC, Alphabet Holdings, XXVI, and Alphabet Inc. may be deemed to indirectly beneficially own (as the term is defined in Rule 13d-3 of the Securities Exchange Act of 1934, as amended) the securities directly beneficially owned by the 2021 Partnership. Each of the aforementioned parties disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein.