Bryan E. Roberts - 17 May 2023 Form 4 Insider Report for 10x Genomics, Inc. (TXG)

Footnote F1

Each share of Class B Common Stock is convertible at any time at the option of the Reporting Person into one share of Class A Common Stock and has no expiration date. Additionally, each share of Class B Common Stock will convert automatically into one share of Class A Common Stock upon transfer, whether or not for value (subject to certain exceptions) and upon the occurrence of certain other events set forth in the Issuer's Amended and Restated Certificate of Incorporation.

Footnote F2

On May 10, 2023, Venrock Associates VI, L.P. ("VA VI") and Venrock Partners VI, L.P. ("VP VI") distributed an aggregate of 1,037,825 shares of Class A Common Stock to their limited partners and general partners. Of the 1,037,825 shares distributed, 962,309 shares were distributed by VA VI to its general partner, Venrock Management VI, LLC ("VM VI") and 75,516 shares were distributed by VP VI to its general partner, Venrock Partners Management VI, LLC ("VPM VI").

Footnote F3

Represents (a) 3,514,480 shares of Class A common stock held by VA VI and (b) 275,942 shares of Class A common stock held by VP VI. VM VI is the sole general partner of VA VI. VPM VI is the sole general partner of VP VI. The Reporting Person is a member of VM VI and VPM VI and disclaims beneficial ownership over all shares held by VA VI and VP VI, except to the extent of his indirect pecuniary interests therein.

Footnote F4

These shares are held by trusts for the benefit of the Reporting Person and his family members.

Footnote F5

On May 12, 2023, the Reporting Person received an aggregate of 83,893 shares of Class A Common Stock as part of the distribution of shares of VM VI and VPM VI.

Footnote F6

Represents (a) 83,893 shares of Class A common stock held directly by the Reporting Person and (b) 2,745 shares of Class A common stock held on behalf of VR Management, LLC (the "Management Company"). The Reporting Person is a member of the Management Company. Under an agreement between the Reporting Person and the Management Company, the Reporting Person is deemed to hold the reported shares for the sole benefit of the Management Company and must exercise the reported shares solely upon the direction of the Management Company, which is entitled to the shares. The Management Company may be deemed the indirect beneficial owner of the reported shares, and the Reporting Person may be deemed the indirect beneficial owner of the reported shares through his interest in the Management Company. The Reporting Person disclaims beneficial ownership of the reported shares except to the extent of his pecuniary interest therein.

Footnote F7

Represents (a) 0 shares of Class B common stock held by VA VI and (b) 0 shares of Class B common stock held by VP VI. VM VI is the sole general partner of VA VI. VPM VI is the sole general partner of VP VI. Dr. Roberts is a member of VM VI and VPM VI and disclaims beneficial ownership over all shares held by VA VI and VP VI, except to the extent of his indirect pecuniary interests therein.