Michael B. Hoffman - 06 Nov 2026 Form 4 Insider Report for Annovis Bio, Inc. (ANVS)

Reporting relationship: Director
Issuer ticker: ANVS
Reported as of: 06 Nov 2026
Net transaction value: +$5,000,000
SEC form: 4
Accepted by SEC: 06 Nov 2026, 16:30:11 UTC
Prior SEC filing: 29 May 2026
Source filing: View source filing
Reporting owner signature: /s/ Maria Maccecchini Attorney-in-Fact

Filing notes and source

Key filing fact

Michael B. Hoffman filed Form 4 for Annovis Bio, Inc. (ANVS) on 06 Nov 2026.

Key facts

This page summarizes Michael B. Hoffman's Form 4 filing for Annovis Bio, Inc. (ANVS).
2 reported transactions and 1 derivative row are listed below.
Accepted by SEC: 06 Nov 2026, 16:30.

Change

Previous filing in this sequence was filed on 29 May 2026.
Current net transaction value: +$5,000,000.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001290208 Primary reporting owner

Hoffman Michael B

Relationship: Director
Address: C/O ANNOVIS BIO, INC., 101 LINDENWOOD DR, SUITE 225, MALVERN
Signature: /s/ Maria Maccecchini Attorney-in-Fact
Signature date: 06 Nov 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

ANVS transaction

Common Stock

Purchase

Transaction value: $5,000,000
Shares: +5,000,000
Change %: +149%
Price: $1.00
Shares after: 8,364,883
Date: 06 Nov 2026
Ownership: Direct
Footnotes: F1

ANVS holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 223,357
Date: 06 Nov 2026
Ownership: The 2024 Hoffman Family Trust
Footnotes: F2

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

ANVS transaction Derivative

Warrants

Purchase

Transaction value
Shares: +5,000,000
Change %
Price: $0.000000^*
Shares after: 5,000,000
Date: 06 Nov 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 5,000,000
Exercise price: $1.00

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 2 footnotes

Footnote F1

The 5,000,000 shares of Common Stock and 5,000,000 warrants described in Table I and Table II, respectively, were acquired for a combined price of $1.00 per share.

Footnote F2

The shares are held in a family trust formed by the reporting person and the reporting person has voting and investment power over such shares.