COLUMN GROUP III GP, LP - 20 Oct 2026 Form 4 Insider Report for Surrozen, Inc./DE (SRZN)

Reporting relationship: 10%+ Owner
Issuer ticker: SRZN
Reported as of: 20 Oct 2026
Net transaction value: $0
SEC form: 4
Accepted by SEC: 22 Oct 2026, 16:48:13 UTC
Prior SEC filing: 26 Feb 2026
Source filing: View source filing
Reporting owner signature: /s/ The Column Group III GP, LP by /s/ James Evangelista, Attorney-in-Fact

Filing notes and source

Key filing fact

COLUMN GROUP III GP, LP filed Form 4 for Surrozen, Inc./DE (SRZN) on 22 Oct 2026.

Key facts

This page summarizes COLUMN GROUP III GP, LP's Form 4 filing for Surrozen, Inc./DE (SRZN).
9 reported transactions and 42 derivative rows are listed below.
Accepted by SEC: 22 Oct 2026, 16:48.

Change

Previous filing in this sequence was filed on 26 Feb 2026.
Current net transaction value: $0.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (7)

CIK 0001790965 Primary reporting owner

COLUMN GROUP III GP, LP

Relationship: 10%+ Owner
Address: 1 LETTERMAN DR., BLDG D, SUITE DM-900, SAN FRANCISCO
Signature: /s/ The Column Group III GP, LP by /s/ James Evangelista, Attorney-in-Fact
Signature date: 22 Oct 2026

CIK 0001668085

COLUMN GROUP III-A, LP

Relationship: 10%+ Owner
Address: 1 LETTERMAN DR., BLDG D, SUITE DM-900, SAN FRANCISCO
Signature: /s/ The Column Group III-A, LP by The Column Group III GP, LP, its general partner /s/ James Evangelista, Attorney-in-Fact
Signature date: 22 Oct 2026

CIK 0001668159

COLUMN GROUP III, LP

Relationship: 10%+ Owner
Address: 1 LETTERMAN DR., BLDG D, SUITE DM-900, SAN FRANCISCO
Signature: /s/ The Column Group III, LP by The Column Group III GP, LP, its general partner /s/ James Evangelista, Attorney-in-Fact
Signature date: 22 Oct 2026

CIK 0001931825

Column Group Opportunity III, LP

Relationship: 10%+ Owner
Address: 1 LETTERMAN DR., BLDG D, SUITE DM-900, SAN FRANCISCO
Signature: /s/ The Column Group Opportunity III, LP by /s/ James Evangelista, Attorney-in-Fact
Signature date: 22 Oct 2026

CIK 0001932874

Column Group Opportunity III GP, LP

Relationship: 10%+ Owner
Address: 1 LETTERMAN DR., BLDG D, SUITE DM-900, SAN FRANCISCO
Signature: /s/ The Column Group Opportunity III GP, LP by /s/ James Evangelista, Attorney-in-Fact
Signature date: 22 Oct 2026

CIK 0001932445

TCG Opportunity III GP, LLC

Relationship: 10%+ Owner
Address: 1 LETTERMAN DR., BLDG D, SUITE DM-900, SAN FRANCISCO
Signature: /s/ TCG Opportunity III GP, LLC by /s/ James Evangelista, Attorney-in-Fact
Signature date: 22 Oct 2026

CIK 0001606074

Svennilson Peter

Relationship: 10%+ Owner
Address: 1 LETTERMAN DR., BLDG D, SUITE DM-900, SAN FRANCISCO
Signature: /s/ James Evangelista, as attorney-in-fact for Peter Svennilson
Signature date: 22 Oct 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +485,830
Change %: +54%
Price: $11.60^*
Shares after: 1,386,122
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Footnotes: F1, F2, F3

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +485,830
Change %: +54%
Price: $11.60^*
Shares after: 1,386,122
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Footnotes: F1, F2, F3

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +485,830
Change %: +54%
Price: $11.60^*
Shares after: 1,386,122
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Footnotes: F1, F2, F3

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +485,830
Change %: +54%
Price: $11.60^*
Shares after: 1,386,122
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Footnotes: F1, F2, F3

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +485,830
Change %: +54%
Price: $11.60^*
Shares after: 1,386,122
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Footnotes: F1, F2, F3

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +485,830
Change %: +54%
Price: $11.60^*
Shares after: 1,386,122
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Footnotes: F1, F2, F3

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +485,830
Change %: +54%
Price: $11.60^*
Shares after: 1,386,122
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Footnotes: F1, F2, F3

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +548,653
Change %: +54%
Price: $11.60^*
Shares after: 1,565,311
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Footnotes: F1, F2, F4

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +548,653
Change %: +54%
Price: $11.60^*
Shares after: 1,565,311
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Footnotes: F1, F2, F4

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +548,653
Change %: +54%
Price: $11.60^*
Shares after: 1,565,311
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Footnotes: F1, F2, F4

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +548,653
Change %: +54%
Price: $11.60^*
Shares after: 1,565,311
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Footnotes: F1, F2, F4

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +548,653
Change %: +54%
Price: $11.60^*
Shares after: 1,565,311
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Footnotes: F1, F2, F4

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +548,653
Change %: +54%
Price: $11.60^*
Shares after: 1,565,311
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Footnotes: F1, F2, F4

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +548,653
Change %: +54%
Price: $11.60^*
Shares after: 1,565,311
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Footnotes: F1, F2, F4

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +517,241
Change %: +150%
Price: $11.60^*
Shares after: 862,068
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Footnotes: F1, F2, F5

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +517,241
Change %: +150%
Price: $11.60^*
Shares after: 862,068
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Footnotes: F1, F2, F5

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +517,241
Change %: +150%
Price: $11.60^*
Shares after: 862,068
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Footnotes: F1, F2, F5

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +517,241
Change %: +150%
Price: $11.60^*
Shares after: 862,068
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Footnotes: F1, F2, F5

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +517,241
Change %: +150%
Price: $11.60^*
Shares after: 862,068
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Footnotes: F1, F2, F5

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +517,241
Change %: +150%
Price: $11.60^*
Shares after: 862,068
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Footnotes: F1, F2, F5

SRZN transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +517,241
Change %: +150%
Price: $11.60^*
Shares after: 862,068
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Footnotes: F1, F2, F5

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -728,745
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Underlying class: Common Stock
Underlying amount: 728,745
Exercise price: $11.60
Footnotes: F1, F2, F3, F6

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -728,745
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Underlying class: Common Stock
Underlying amount: 728,745
Exercise price: $11.60
Footnotes: F1, F2, F3, F6

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -728,745
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Underlying class: Common Stock
Underlying amount: 728,745
Exercise price: $11.60
Footnotes: F1, F2, F3, F6

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -728,745
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Underlying class: Common Stock
Underlying amount: 728,745
Exercise price: $11.60
Footnotes: F1, F2, F3, F6

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -728,745
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Underlying class: Common Stock
Underlying amount: 728,745
Exercise price: $11.60
Footnotes: F1, F2, F3, F6

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -728,745
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Underlying class: Common Stock
Underlying amount: 728,745
Exercise price: $11.60
Footnotes: F1, F2, F3, F6

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -728,745
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Underlying class: Common Stock
Underlying amount: 728,745
Exercise price: $11.60
Footnotes: F1, F2, F3, F6

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -822,980
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Underlying class: Common Stock
Underlying amount: 822,980
Exercise price: $11.60
Footnotes: F1, F2, F4, F7

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -822,980
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Underlying class: Common Stock
Underlying amount: 822,980
Exercise price: $11.60
Footnotes: F1, F2, F4, F7

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -822,980
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Underlying class: Common Stock
Underlying amount: 822,980
Exercise price: $11.60
Footnotes: F1, F2, F4, F7

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -822,980
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Underlying class: Common Stock
Underlying amount: 822,980
Exercise price: $11.60
Footnotes: F1, F2, F4, F7

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -822,980
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Underlying class: Common Stock
Underlying amount: 822,980
Exercise price: $11.60
Footnotes: F1, F2, F4, F7

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -822,980
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Underlying class: Common Stock
Underlying amount: 822,980
Exercise price: $11.60
Footnotes: F1, F2, F4, F7

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -822,980
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Underlying class: Common Stock
Underlying amount: 822,980
Exercise price: $11.60
Footnotes: F1, F2, F4, F7

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -775,861
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Underlying class: Common Stock
Underlying amount: 775,861
Exercise price: $11.60
Footnotes: F1, F2, F5, F8

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -775,861
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Underlying class: Common Stock
Underlying amount: 775,861
Exercise price: $11.60
Footnotes: F1, F2, F5, F8

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -775,861
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Underlying class: Common Stock
Underlying amount: 775,861
Exercise price: $11.60
Footnotes: F1, F2, F5, F8

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -775,861
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Underlying class: Common Stock
Underlying amount: 775,861
Exercise price: $11.60
Footnotes: F1, F2, F5, F8

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -775,861
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Underlying class: Common Stock
Underlying amount: 775,861
Exercise price: $11.60
Footnotes: F1, F2, F5, F8

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -775,861
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Underlying class: Common Stock
Underlying amount: 775,861
Exercise price: $11.60
Footnotes: F1, F2, F5, F8

SRZN transaction Derivative

Second Tranche Units (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: -775,861
Change %: -100%
Price
Shares after: 0
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Underlying class: Common Stock
Underlying amount: 775,861
Exercise price: $11.60
Footnotes: F1, F2, F5, F8

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +242,915
Change %: +150%
Price
Shares after: 404,858
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Underlying class: Common Stock
Underlying amount: 242,915
Exercise price: $11.54
Footnotes: F1, F3, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +242,915
Change %: +150%
Price
Shares after: 404,858
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Underlying class: Common Stock
Underlying amount: 242,915
Exercise price: $11.54
Footnotes: F1, F3, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +242,915
Change %: +150%
Price
Shares after: 404,858
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Underlying class: Common Stock
Underlying amount: 242,915
Exercise price: $11.54
Footnotes: F1, F3, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +242,915
Change %: +150%
Price
Shares after: 404,858
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Underlying class: Common Stock
Underlying amount: 242,915
Exercise price: $11.54
Footnotes: F1, F3, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +242,915
Change %: +150%
Price
Shares after: 404,858
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Underlying class: Common Stock
Underlying amount: 242,915
Exercise price: $11.54
Footnotes: F1, F3, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +242,915
Change %: +150%
Price
Shares after: 404,858
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Underlying class: Common Stock
Underlying amount: 242,915
Exercise price: $11.54
Footnotes: F1, F3, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +242,915
Change %: +150%
Price
Shares after: 404,858
Date: 20 Oct 2026
Ownership: By The Column Group III, LP
Underlying class: Common Stock
Underlying amount: 242,915
Exercise price: $11.54
Footnotes: F1, F3, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +274,327
Change %: +150%
Price
Shares after: 457,211
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Underlying class: Common Stock
Underlying amount: 274,327
Exercise price: $11.54
Footnotes: F1, F4, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +274,327
Change %: +150%
Price
Shares after: 457,211
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Underlying class: Common Stock
Underlying amount: 274,327
Exercise price: $11.54
Footnotes: F1, F4, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +274,327
Change %: +150%
Price
Shares after: 457,211
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Underlying class: Common Stock
Underlying amount: 274,327
Exercise price: $11.54
Footnotes: F1, F4, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +274,327
Change %: +150%
Price
Shares after: 457,211
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Underlying class: Common Stock
Underlying amount: 274,327
Exercise price: $11.54
Footnotes: F1, F4, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +274,327
Change %: +150%
Price
Shares after: 457,211
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Underlying class: Common Stock
Underlying amount: 274,327
Exercise price: $11.54
Footnotes: F1, F4, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +274,327
Change %: +150%
Price
Shares after: 457,211
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Underlying class: Common Stock
Underlying amount: 274,327
Exercise price: $11.54
Footnotes: F1, F4, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +274,327
Change %: +150%
Price
Shares after: 457,211
Date: 20 Oct 2026
Ownership: By The Column Group III-A, LP
Underlying class: Common Stock
Underlying amount: 274,327
Exercise price: $11.54
Footnotes: F1, F4, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +258,620
Change %: +150%
Price
Shares after: 431,034
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Underlying class: Common Stock
Underlying amount: 258,620
Exercise price: $11.54
Footnotes: F1, F5, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +258,620
Change %: +150%
Price
Shares after: 431,034
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Underlying class: Common Stock
Underlying amount: 258,620
Exercise price: $11.54
Footnotes: F1, F5, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +258,620
Change %: +150%
Price
Shares after: 431,034
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Underlying class: Common Stock
Underlying amount: 258,620
Exercise price: $11.54
Footnotes: F1, F5, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +258,620
Change %: +150%
Price
Shares after: 431,034
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Underlying class: Common Stock
Underlying amount: 258,620
Exercise price: $11.54
Footnotes: F1, F5, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +258,620
Change %: +150%
Price
Shares after: 431,034
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Underlying class: Common Stock
Underlying amount: 258,620
Exercise price: $11.54
Footnotes: F1, F5, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +258,620
Change %: +150%
Price
Shares after: 431,034
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Underlying class: Common Stock
Underlying amount: 258,620
Exercise price: $11.54
Footnotes: F1, F5, F9

SRZN transaction Derivative

Series E Common Warrants

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares: +258,620
Change %: +150%
Price
Shares after: 431,034
Date: 20 Oct 2026
Ownership: By The Column Group Opportunity III, LP
Underlying class: Common Stock
Underlying amount: 258,620
Exercise price: $11.54
Footnotes: F1, F5, F9

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 9 footnotes

Footnote F1

Each Second Tranche Unit consists of (a) one share of the Issuer's Common Stock and (b) one half of a Series E Common Warrant to purchase shares of Common Stock. The Second Tranche Units were purchased in the Issuer's private placement on October 20, 2026 (the "2026 Private Placement").

Footnote F2

Represents a price per unit, consisting of (i) $11.5375 per share of the Issuer's Common Stock and (ii) $0.0625 attributable to accompanying warrants to purchase shares of the Issuer's Common Stock, which The Column Group III, LP ("TCG III LP"), The Column Group III-A, LP ("TCG III-A LP") and The Column Group Opportunity III, LP ("TCG Opportunity III LP") purchased in the Issuer's 2026 Private Placement.

Footnote F3

The securities are directly held by The Column Group III, LP ("TCG III LP"). The Column Group III GP, LP ("TCG III GP") is the general partner of TCG III LP and may be deemed to have voting, investment and dispositive power with respect to these securities. The managing partners of TCG III GP are Peter Svennilson and Tim Kutzkey, a member of the Issuer's board of directors (collectively, the "Managing Partners"). The Managing Partners may be deemed to share voting and investment power with respect to such securities. TCG III GP and each of the Managing Partners disclaim beneficial ownership of these securities, except to the extent of their respective pecuniary interest in such securities.

Footnote F4

The securities are directly held by The Column Group III-A, LP ("TCG III-A LP"). TCG III GP is the general partner of TCG III-A LP and may be deemed to have voting, investment and dispositive power with respect to these securities. The managing partners of TCG III GP are the Managing Partners. The Managing Partners may be deemed to share voting and investment power with respect to such securities. TCG III GP and each of the Managing Partners disclaim beneficial ownership of these securities, except to the extent of their respective pecuniary interest in such securities.

Footnote F5

The securities are directly held by The Column Group Opportunity III, LP ("TCG Opportunity III LP"). The Column Group Opportunity III GP, LP ("TCG Opportunity III GP LP") is the general partner of TCG Opportunity III LP and may be deemed to have voting, investment and dispositive power with respect to these securities. TCG Opportunity III GP, LLC ("TCG Opportunity III GP LLC") is the general partner of TCG Opportunity III GP LP and the ultimate general partner of TCG Opportunity III LP and may be deemed to have voting, investment and dispositive power with respect to these securities. The managing members of TCG Opportunity III GP LLC are the Managing Partners. TCG Opportunity III GP LP, TCG Opportunity III GP LLC and each of the Managing Partners disclaim beneficial ownership of these securities, except to the extent of their respective pecuniary interest in such securities.

Footnote F6

Consists of (a) 485,830 shares of the Issuer's Common Stock and (b) 242,915 Series E Common Warrants to purchase shares of the Issuer's Common Stock.

Footnote F7

Consists of (a) 548,653 shares of the Issuer's Common Stock and (b) 274,327 Series E Common Warrants to purchase shares of the Issuer's Common Stock.

Footnote F8

Consists of (a) 517,241 shares of the Issuer's Common Stock and (b) 258,620 Series E Common Warrants to purchase shares of the Issuer's Common Stock.

Footnote F9

These Series E Common Warrants are exercisable immediately and will not expire until exercised in full (subject to certain beneficial ownership limitations).

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