Joshua J. Ofman - 21 Sep 2026 Form 4 Insider Report for GRAIL, Inc. (GRAL)

Reporting relationship: Chief Executive Officer, Director
Issuer ticker: GRAL
Reported as of: 21 Sep 2026
Net transaction value: -$6,006,378
SEC form: 4
Accepted by SEC: 23 Sep 2026, 16:37:03 UTC
Prior SEC filing: 31 Aug 2026
Next SEC filing: 16 Oct 2026
Source filing: View source filing
Reporting owner signature: /s/Abram Barth, as Attorney-in-Fact for Joshua Ofman

Filing notes and source

Key filing fact

Joshua J. Ofman filed Form 4 for GRAIL, Inc. (GRAL) on 23 Sep 2026.

Key facts

This page summarizes Joshua J. Ofman's Form 4 filing for GRAIL, Inc. (GRAL).
10 reported transactions and 1 derivative row are listed below.
Accepted by SEC: 23 Sep 2026, 16:37.

Change

Previous filing in this sequence was filed on 31 Aug 2026.
Current net transaction value: -$6,006,378.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001822088 Primary reporting owner

Ofman Joshua J.

Relationship: Chief Executive Officer, Director
Address: C/O GRAIL, INC., 250 S. MATHILDA AVE. SUITE 100, SUNNYVALE
Signature: /s/Abram Barth, as Attorney-in-Fact for Joshua Ofman
Signature date: 23 Sep 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

GRAL transaction

Common Stock

Options Exercise

Transaction value
Shares: +26,452
Change %: +6.7%
Price: $14.00^*
Shares after: 423,723
Date: 21 Sep 2026
Ownership: Direct

GRAL transaction

Common Stock

Sale

Transaction value: $196,170
Shares: -2,125
Change %: -0.5%
Price: $92.32
Shares after: 421,598
Date: 21 Sep 2026
Ownership: Direct
Footnotes: F1, F2

GRAL transaction

Common Stock

Sale

Transaction value: $136,103
Shares: -1,454
Change %: -0.34%
Price: $93.61
Shares after: 420,144
Date: 21 Sep 2026
Ownership: Direct
Footnotes: F1, F3

GRAL transaction

Common Stock

Sale

Transaction value: $3,585,791
Shares: -37,752
Change %: -9%
Price: $94.98
Shares after: 382,392
Date: 21 Sep 2026
Ownership: Direct
Footnotes: F1, F4

GRAL transaction

Common Stock

Sale

Transaction value: $597,871
Shares: -6,200
Change %: -1.6%
Price: $96.43
Shares after: 376,192
Date: 21 Sep 2026
Ownership: Direct
Footnotes: F1, F5

GRAL transaction

Common Stock

Sale

Transaction value: $136,978
Shares: -1,400
Change %: -0.37%
Price: $97.84
Shares after: 374,792
Date: 21 Sep 2026
Ownership: Direct
Footnotes: F1, F6

GRAL transaction

Common Stock

Sale

Transaction value: $42,037
Shares: -421
Change %: -0.11%
Price: $99.85
Shares after: 374,371
Date: 21 Sep 2026
Ownership: Direct
Footnotes: F1, F7

GRAL transaction

Common Stock

Sale

Transaction value: $211,429
Shares: -2,100
Change %: -0.56%
Price: $100.68
Shares after: 372,271
Date: 21 Sep 2026
Ownership: Direct
Footnotes: F1, F8

GRAL transaction

Common Stock

Sale

Transaction value: $1,100,000
Shares: -10,000
Change %: -2.7%
Price: $110.00
Shares after: 362,271
Date: 21 Sep 2026
Ownership: Direct
Footnotes: F1

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

GRAL transaction Derivative

Stock Option

Options Exercise

Transaction value
Shares: -26,452
Change %: -42%
Price: $0.000000^*
Shares after: 37,032
Date: 21 Sep 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 26,452
Exercise price: $14.00
Footnotes: F9

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Rule 10b5-1 trading plan

These transactions were reported as open-market trades under a Rule 10b5-1 plan. The plan lets an insider set trading instructions in advance, which can reduce the risk of trading while in possession of material nonpublic information.

Original filing language: transaction made pursuant to a contract, instruction, or written plan intended to satisfy Rule 10b5-1(c).

Explanation of responses 9 footnotes

Footnote F1

The sale transactions reported in this Form 4 are made pursuant to a Rule 10b5-1 trading plan adopted on December 2, 2025

Footnote F2

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $92.04 to $92.93 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate sales price within the range set forth in this footnote

Footnote F3

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $93.04 to $93.90 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate sales price within the range set forth in this footnote

Footnote F4

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $94.5 to $95.00 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate sales price within the range set forth in this footnote

Footnote F5

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $96.00 to $96.71 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate sales price within the range set forth in this footnote

Footnote F6

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $97.74 to $98.00 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate sales price within the range set forth in this footnote

Footnote F7

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $99.42 to $100.28 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate sales price within the range set forth in this footnote

Footnote F8

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $100.68 to $100.69 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate sales price within the range set forth in this footnote

Footnote F9

Represents an option originally granted on March 6, 2020 for which the performance condition was determined to be met on November 1, 2024. The option vests and becomes exercisable in thirty-six substantially equal monthly installments beginning December 1, 2024. As of September 21, 2026, approximately 61% of the shares subject to the option had vested, and the remaining approximately 39% of the shares vests over the remaining period afterwards.