Crespo Blas Coll - 18 Sep 2026 Form 4 Insider Report for Structure Therapeutics Inc. (GPCR)

Reporting relationship: CHIEF MEDICAL OFFICER
Issuer ticker: GPCR
Reported as of: 18 Sep 2026
Net transaction value: -$144,873
SEC form: 4
Accepted by SEC: 22 Sep 2026, 17:59:49 UTC
Prior SEC filing: 23 Mar 2026
Source filing: View source filing
Reporting owner signature: /s/ Jun Yoon, Attorney-in-Fact

Key filing fact

Crespo Blas Coll filed Form 4 for Structure Therapeutics Inc. (GPCR) on 22 Sep 2026.

Key facts

This page summarizes Crespo Blas Coll's Form 4 filing for Structure Therapeutics Inc. (GPCR).
4 reported transactions and 2 derivative rows are listed below.
Accepted by SEC: 22 Sep 2026, 17:59.

Change

Previous filing in this sequence was filed on 23 Mar 2026.
Current net transaction value: -$144,873.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0002037144 Primary reporting owner

Coll Crespo Blas

Relationship: CHIEF MEDICAL OFFICER
Address: C/O STRUCTURE THERAPEUTICS INC., 601 GATEWAY BLVD., SUITE 900, SOUTH SAN FRANCISCO
Signature: /s/ Jun Yoon, Attorney-in-Fact
Signature date: 22 Sep 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

GPCR transaction

Ordinary Shares

Tax liability

Transaction value
Shares: -10,626
Change %: -3.8%
Price: $11.67^*
Shares after: 270,252
Date: 18 Sep 2026
Ownership: Direct
Footnotes: F1, F2, F3

GPCR transaction

Ordinary Shares

Conversion of derivative security

Transaction value
Shares: -12,024
Change %: -4.4%
Price: $0.000000^*
Shares after: 258,228
Date: 21 Sep 2026
Ownership: Direct
Footnotes: F4

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

GPCR transaction Derivative

American Depositary Shares

Conversion of derivative security

Transaction value
Shares: +4,008
Change %: +346%
Price: $0.000000^*
Shares after: 5,165
Date: 21 Sep 2026
Ownership: Direct
Underlying class: Ordinary Shares
Underlying amount: 12,024
Exercise price
Footnotes: F4, F5

GPCR transaction Derivative

American Depositary Shares

Sale

Transaction value: $144,873
Shares: -4,008
Change %: -78%
Price: $36.15
Shares after: 1,157
Date: 21 Sep 2026
Ownership: Direct
Underlying class: Ordinary Shares
Underlying amount: 12,024
Exercise price
Footnotes: F5, F6

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Rule 10b5-1 trading plan

These transactions were reported as open-market trades under a Rule 10b5-1 plan. The plan lets an insider set trading instructions in advance, which can reduce the risk of trading while in possession of material nonpublic information.

Original filing language: transaction made pursuant to a contract, instruction, or written plan intended to satisfy Rule 10b5-1(c).

Explanation of responses 6 footnotes

Footnote F1

The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

Footnote F2

Represents shares withheld by the Issuer to satisfy income tax obligations associated with the vesting of a restricted share unit award.

Footnote F3

Reflects price per share in Ordinary Shares.

Footnote F4

12,024 Ordinary Shares were converted into 4,008 American Depositary Shares as reported in Table II.

Footnote F5

Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date.

Footnote F6

The American Depositary Shares were sold pursuant to a Rule 10b5-1 trading plan entered into on March 30, 2026.