William John Sibold - 09 Sep 2026 Form 4 Insider Report for MADRIGAL PHARMACEUTICALS, INC. (MDGL)

Reporting relationship: President and CEO, Director
Issuer ticker: MDGL
Reported as of: 09 Sep 2026
Net transaction value: -$6,239,198
SEC form: 4
Accepted by SEC: 11 Sep 2026, 16:57:12 UTC
Prior SEC filing: 20 Jul 2026
Source filing: View source filing
Reporting owner signature: /s/ Mardi Dier, as Attorney-in-Fact

Key filing fact

William John Sibold filed Form 4 for MADRIGAL PHARMACEUTICALS, INC. (MDGL) on 11 Sep 2026.

Key facts

This page summarizes William John Sibold's Form 4 filing for MADRIGAL PHARMACEUTICALS, INC. (MDGL).
24 reported transactions and 0 derivative rows are listed below.
Accepted by SEC: 11 Sep 2026, 16:57.

Change

Previous filing in this sequence was filed on 20 Jul 2026.
Current net transaction value: -$6,239,198.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001518611 Primary reporting owner

Sibold William John

Relationship: President and CEO, Director
Address: C/O MADRIGAL PHARMACEUTICALS, INC., 1001 CONSHOHOCKEN STATE ROAD SUITE 2-350, WEST CONSHOHOCKEN
Signature: /s/ Mardi Dier, as Attorney-in-Fact
Signature date: 11 Sep 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

MDGL transaction

Common Stock

Sale

Transaction value: $69,152
Shares: -131
Change %: -0.06%
Price: $527.88
Shares after: 209,198
Date: 09 Sep 2026
Ownership: Direct
Footnotes: F1, F2

MDGL transaction

Common Stock

Sale

Transaction value: $183,656
Shares: -347
Change %: -0.17%
Price: $529.27
Shares after: 208,851
Date: 09 Sep 2026
Ownership: Direct
Footnotes: F1, F3

MDGL transaction

Common Stock

Sale

Transaction value: $276,781
Shares: -522
Change %: -0.25%
Price: $530.23
Shares after: 208,329
Date: 09 Sep 2026
Ownership: Direct
Footnotes: F1, F4

MDGL transaction

Common Stock

Sale

Transaction value: $195,772
Shares: -368
Change %: -0.18%
Price: $531.99
Shares after: 207,961
Date: 09 Sep 2026
Ownership: Direct
Footnotes: F1, F5

MDGL transaction

Common Stock

Sale

Transaction value: $272,944
Shares: -512
Change %: -0.25%
Price: $533.09
Shares after: 207,449
Date: 09 Sep 2026
Ownership: Direct
Footnotes: F1, F6

MDGL transaction

Common Stock

Sale

Transaction value: $211,542
Shares: -396
Change %: -0.19%
Price: $534.20
Shares after: 207,053
Date: 09 Sep 2026
Ownership: Direct
Footnotes: F1, F7

MDGL transaction

Common Stock

Sale

Transaction value: $344,715
Shares: -644
Change %: -0.31%
Price: $535.27
Shares after: 206,409
Date: 09 Sep 2026
Ownership: Direct
Footnotes: F1, F8

MDGL transaction

Common Stock

Sale

Transaction value: $557,557
Shares: -1,040
Change %: -0.5%
Price: $536.11
Shares after: 205,369
Date: 09 Sep 2026
Ownership: Direct
Footnotes: F1, F9

MDGL transaction

Common Stock

Sale

Transaction value: $343,791
Shares: -640
Change %: -0.31%
Price: $537.17
Shares after: 204,729
Date: 09 Sep 2026
Ownership: Direct
Footnotes: F1, F10

MDGL transaction

Common Stock

Sale

Transaction value: $279,914
Shares: -520
Change %: -0.25%
Price: $538.30
Shares after: 204,209
Date: 09 Sep 2026
Ownership: Direct
Footnotes: F1, F11

MDGL transaction

Common Stock

Sale

Transaction value: $115,891
Shares: -215
Change %: -0.11%
Price: $539.03
Shares after: 203,994
Date: 09 Sep 2026
Ownership: Direct
Footnotes: F1, F12

MDGL transaction

Common Stock

Sale

Transaction value: $272,796
Shares: -505
Change %: -0.25%
Price: $540.19
Shares after: 203,489
Date: 09 Sep 2026
Ownership: Direct
Footnotes: F1, F13

MDGL transaction

Common Stock

Sale

Transaction value: $196,079
Shares: -362
Change %: -0.18%
Price: $541.65
Shares after: 203,127
Date: 09 Sep 2026
Ownership: Direct
Footnotes: F1, F14

MDGL transaction

Common Stock

Sale

Transaction value: $86,808
Shares: -160
Change %: -0.08%
Price: $542.55
Shares after: 202,967
Date: 09 Sep 2026
Ownership: Direct
Footnotes: F1, F15

MDGL transaction

Common Stock

Sale

Transaction value: $31,985
Shares: -60
Change %: -0.03%
Price: $533.09
Shares after: 202,907
Date: 11 Sep 2026
Ownership: Direct
Footnotes: F16, F17

MDGL transaction

Common Stock

Sale

Transaction value: $56,611
Shares: -106
Change %: -0.05%
Price: $534.06
Shares after: 202,801
Date: 11 Sep 2026
Ownership: Direct
Footnotes: F16, F18

MDGL transaction

Common Stock

Sale

Transaction value: $116,836
Shares: -218
Change %: -0.11%
Price: $535.94
Shares after: 202,583
Date: 11 Sep 2026
Ownership: Direct
Footnotes: F16, F19

MDGL transaction

Common Stock

Sale

Transaction value: $86,019
Shares: -160
Change %: -0.08%
Price: $537.62
Shares after: 202,423
Date: 11 Sep 2026
Ownership: Direct
Footnotes: F16, F20

MDGL transaction

Common Stock

Sale

Transaction value: $371,382
Shares: -687
Change %: -0.34%
Price: $540.59
Shares after: 201,736
Date: 11 Sep 2026
Ownership: Direct
Footnotes: F16, F21

MDGL transaction

Common Stock

Sale

Transaction value: $199,324
Shares: -368
Change %: -0.18%
Price: $541.64
Shares after: 201,368
Date: 11 Sep 2026
Ownership: Direct
Footnotes: F16, F22

MDGL transaction

Common Stock

Sale

Transaction value: $652,209
Shares: -1,202
Change %: -0.6%
Price: $542.60
Shares after: 200,166
Date: 11 Sep 2026
Ownership: Direct
Footnotes: F16, F23

MDGL transaction

Common Stock

Sale

Transaction value: $837,253
Shares: -1,539
Change %: -0.77%
Price: $544.02
Shares after: 198,627
Date: 11 Sep 2026
Ownership: Direct
Footnotes: F16, F24

MDGL transaction

Common Stock

Sale

Transaction value: $414,616
Shares: -761
Change %: -0.38%
Price: $544.83
Shares after: 197,866
Date: 11 Sep 2026
Ownership: Direct
Footnotes: F16, F25

MDGL transaction

Common Stock

Sale

Transaction value: $65,565
Shares: -120
Change %: -0.06%
Price: $546.38
Shares after: 197,746
Date: 11 Sep 2026
Ownership: Direct
Footnotes: F16, F26

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Rule 10b5-1 trading plan

These transactions were reported as open-market trades under a Rule 10b5-1 plan. The plan lets an insider set trading instructions in advance, which can reduce the risk of trading while in possession of material nonpublic information.

Original filing language: transaction made pursuant to a contract, instruction, or written plan intended to satisfy Rule 10b5-1(c).

Explanation of responses 26 footnotes

Footnote F1

This sale represents the number of shares sold by the Issuer on behalf of the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. This sale was automatic and not at the discretion of the Reporting Person.

Footnote F2

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $527.49 to $528.27, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote and the footnotes below.

Footnote F3

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $528.54 to $529.51, inclusive.

Footnote F4

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $529.64 to $530.48, inclusive.

Footnote F5

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $531.57 to $532.28, inclusive.

Footnote F6

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $532.57 to $533.29, inclusive.

Footnote F7

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $533.58 to $534.57, inclusive.

Footnote F8

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $534.63 to $535.62, inclusive.

Footnote F9

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $535.64 to $536.45, inclusive.

Footnote F10

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $536.64 to $537.56, inclusive.

Footnote F11

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $537.70 to $538.65, inclusive.

Footnote F12

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $538.86 to $539.83, inclusive.

Footnote F13

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $539.86 to $540.47, inclusive.

Footnote F14

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $541.29 to $542.27, inclusive.

Footnote F15

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $542.42 to $542.68, inclusive.

Footnote F16

These sales were effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 5, 2026.

Footnote F17

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $532.76 to $533.64, inclusive.

Footnote F18

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $533.76 to $534.48, inclusive.

Footnote F19

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $535.52 to $536.02, inclusive.

Footnote F20

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $537.235 to $538.00, inclusive.

Footnote F21

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $539.97 to $540.90, inclusive.

Footnote F22

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $541.00 to $541.73, inclusive.

Footnote F23

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $542.11 to $543.02, inclusive.

Footnote F24

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $543.27 to $544.20, inclusive.

Footnote F25

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $544.38 to $545.32, inclusive.

Footnote F26

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $546.28 to $546.56, inclusive.