Michael Vincent Meluzio - 13 Aug 2026 Form 4 Insider Report for Cue Biopharma, Inc. (CUE)

Reporting relationship: VP, Prin. Accounting Officer
Issuer ticker: CUE
Reported as of: 13 Aug 2026
Net transaction value: -$169,324
SEC form: 4
Accepted by SEC: 17 Aug 2026, 18:19:56 UTC
Prior SEC filing: 10 Jul 2026
Source filing: View source filing
Reporting owner signature: /s/ Michael Meluzio

Key filing fact

Michael Vincent Meluzio filed Form 4 for Cue Biopharma, Inc. (CUE) on 17 Aug 2026.

Key facts

This page summarizes Michael Vincent Meluzio's Form 4 filing for Cue Biopharma, Inc. (CUE).
5 reported transactions and 1 derivative row are listed below.
Accepted by SEC: 17 Aug 2026, 18:19.

Change

Previous filing in this sequence was filed on 10 Jul 2026.
Current net transaction value: -$169,324.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0002138368 Primary reporting owner

Meluzio Michael Vincent

Relationship: VP, Prin. Accounting Officer
Address: C/O CUE BIOPHARMA, INC., 40 GUEST STREET, BOSTON
Signature: /s/ Michael Meluzio
Signature date: 17 Aug 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

CUE transaction

Common Stock

Options Exercise

Transaction value
Shares: +13,647
Change %: +33%
Price: $0.000000^*
Shares after: 54,589
Date: 13 Aug 2026
Ownership: Direct

CUE transaction

Common Stock

Sale

Transaction value: $44,613
Shares: -1,519
Change %: -2.8%
Price: $29.37
Shares after: 53,070
Date: 13 Aug 2026
Ownership: Direct
Footnotes: F1, F2

CUE transaction

Common Stock

Sale

Transaction value: $124,617
Shares: -4,106
Change %: -7.7%
Price: $30.35
Shares after: 48,964
Date: 13 Aug 2026
Ownership: Direct
Footnotes: F1, F3

CUE transaction

Common Stock

Sale

Transaction value: $93.39
Shares: -3
Change %: -0.01%
Price: $31.13
Shares after: 48,961
Date: 13 Aug 2026
Ownership: Direct
Footnotes: F1

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

CUE transaction Derivative

Common Stock

Options Exercise

Transaction value
Shares: -13,647
Change %: -33%
Price: $0.000000^*
Shares after: 27,295
Date: 13 Aug 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 13,647
Exercise price
Footnotes: F4

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 4 footnotes

Footnote F1

The sales reported represents shares sold by the Reporting Person to cover tax withholding obligations in connection with the vesting and settlement of restricted stock units. The sales were to satisfy tax withholding obligations to be funded by a "sell-to-cover" transaction and do not represent discretionary transactions by the reporting person.

Footnote F2

The price reported in this line item is a weighted average price. These shares were sold as part of block trades for multiple security holders of the Issuer at prices ranging from $28.97 to $29.96, inclusive. The Reporting Person undertakes to provide to the Issuer, any securityholder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth herein to the block trades.

Footnote F3

The price reported in this line item is a weighted average price. These shares were sold as part of block trades for multiple security holders of the Issuer at prices ranging from $29.99 to $30.97, inclusive. The Reporting Person undertakes to provide to the Issuer, any securityholder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth herein to the block trades.

Footnote F4

The performance stock units ("PSU") were awarded subject to certain stock-price based vesting conditions with vesting comprised of three substantially equal tranches that are eligible to vest based the achievement of a closing price per share of $33.00, $38.50 and $44.00, in each case for a period of five consecutive trading days. If the stock price targets are not satisfied by the period ending 24 months from the date of grant, the PSUs shall automatically be forfeited and cancelled without consideration. The award settled with respect to 1/3 of the PSUs underlying the award on August 13, 2026. The remaining 2/3 of the PSUs underlying the award are expected to settle on the achievement of a closing price per share of $38.50 and $44.00, in each case for a period of five consecutive trading days.