RA CAPITAL MANAGEMENT, L.P. - 20 Jul 2026 Form 4 Insider Report for Freenome, Inc. (PCSC)

Reporting relationship: Director, 10%+ Owner
Issuer ticker: PCSC
Reported as of: 20 Jul 2026
Net transaction value: $0
SEC form: 4
Accepted by SEC: 22 Jul 2026, 17:31:04 UTC
Prior SEC filing: 20 Jul 2026
Next SEC filing: 23 Jul 2026
Source filing: View source filing
Reporting owner signature: /s/ Peter Kolchinsky, Manager of RA Capital Management, L.P.

Key filing fact

RA CAPITAL MANAGEMENT, L.P. filed Form 4 for Freenome, Inc. (PCSC) on 22 Jul 2026.

Key facts

This page summarizes RA CAPITAL MANAGEMENT, L.P.'s Form 4 filing for Freenome, Inc. (PCSC).
7 reported transactions and 0 derivative rows are listed below.
Accepted by SEC: 22 Jul 2026, 17:31.

Change

Previous filing in this sequence was filed on 20 Jul 2026.
Current net transaction value: $0.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (7)

CIK 0001346824 Primary reporting owner

RA CAPITAL MANAGEMENT, L.P.

Relationship: Director, 10%+ Owner
Address: 200 BERKELEY STREET, 18TH FLOOR, BOSTON
Signature: /s/ Peter Kolchinsky, Manager of RA Capital Management, L.P.
Signature date: 22 Jul 2026

CIK 0001315082

RA Capital Healthcare Fund LP

Relationship: Director, 10%+ Owner
Address: C/O RA CAPITAL MANAGEMENT, L.P., 200 BERKELEY STREET, 18TH FLOOR, BOSTON
Signature: /s/ Peter Kolchinsky, Manager of RA Capital Healthcare Fund GP, LLC, the General Partner of RA Capital Healthcare Fund, L.P.
Signature date: 22 Jul 2026

CIK 0001780117

RA Capital Nexus Fund, L.P.

Relationship: Director
Address: C/O RA CAPITAL MANAGEMENT, L.P., 200 BERKELEY STREET, 18TH FLOOR, BOSTON
Signature: /s/ Peter Kolchinsky, Manager of RA Capital Nexus Fund GP, LLC, the General Partner of RA Capital Nexus Fund, L.P.
Signature date: 22 Jul 2026

CIK 0001825376

RA Capital Nexus Fund II, L.P.

Relationship: Director
Address: C/O RA CAPITAL MANAGEMENT, L.P., 200 BERKELEY STREET, 18TH FLOOR, BOSTON
Signature: /s/ Peter Kolchinsky, Manager of RA Capital Nexus Fund II GP, LLC, the General Partner of RA Capital Nexus Fund II, L.P.
Signature date: 22 Jul 2026

CIK 0001883840

RA Capital Nexus Fund III, L.P.

Relationship: Director
Address: C/O RA CAPITAL MANAGEMENT, L.P., 200 BERKELEY STREET, 18TH FLOOR, BOSTON
Signature: /s/ Peter Kolchinsky, Manager of RA Capital Nexus Fund III GP, LLC, the General Partner of RA Capital Nexus Fund III, L.P.
Signature date: 22 Jul 2026

CIK 0001384859

Kolchinsky Peter

Relationship: Director, 10%+ Owner
Address: C/O RA CAPITAL MANAGEMENT, L.P., 200 BERKELEY STREET, 18TH FLOOR, BOSTON
Signature: /s/ Peter Kolchinsky, individually
Signature date: 22 Jul 2026

CIK 0001619841

Shah Rajeev M.

Relationship: Director, 10%+ Owner
Address: C/O RA CAPITAL MANAGEMENT, L.P., 200 BERKELEY STREET, 18TH FLOOR, BOSTON
Signature: /s/ Rajeev Shah, individually
Signature date: 22 Jul 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

PCSC transaction

Common Stock

Award

Transaction value
Shares: +6,561,711
Change %: +875%
Price
Shares after: 7,311,711
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F2, F3, F4

PCSC transaction

Common Stock

Award

Transaction value
Shares: +6,561,711
Change %: +875%
Price
Shares after: 7,311,711
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F2, F3, F4

PCSC transaction

Common Stock

Award

Transaction value
Shares: +6,561,711
Change %: +875%
Price
Shares after: 7,311,711
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F2, F3, F4

PCSC transaction

Common Stock

Award

Transaction value
Shares: +6,561,711
Change %: +875%
Price
Shares after: 7,311,711
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F2, F3, F4

PCSC transaction

Common Stock

Award

Transaction value
Shares: +6,561,711
Change %: +875%
Price
Shares after: 7,311,711
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F2, F3, F4

PCSC transaction

Common Stock

Award

Transaction value
Shares: +6,561,711
Change %: +875%
Price
Shares after: 7,311,711
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F2, F3, F4

PCSC transaction

Common Stock

Award

Transaction value
Shares: +6,561,711
Change %: +875%
Price
Shares after: 7,311,711
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F2, F3, F4

PCSC transaction

Common Stock

Award

Transaction value
Shares: +970,950
Change %
Price
Shares after: 970,950
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F5, F6

PCSC transaction

Common Stock

Award

Transaction value
Shares: +970,950
Change %
Price
Shares after: 970,950
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F5, F6

PCSC transaction

Common Stock

Award

Transaction value
Shares: +970,950
Change %
Price
Shares after: 970,950
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F5, F6

PCSC transaction

Common Stock

Award

Transaction value
Shares: +970,950
Change %
Price
Shares after: 970,950
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F5, F6

PCSC transaction

Common Stock

Award

Transaction value
Shares: +970,950
Change %
Price
Shares after: 970,950
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F5, F6

PCSC transaction

Common Stock

Award

Transaction value
Shares: +970,950
Change %
Price
Shares after: 970,950
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F5, F6

PCSC transaction

Common Stock

Award

Transaction value
Shares: +970,950
Change %
Price
Shares after: 970,950
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F5, F6

PCSC transaction

Common Stock

Award

Transaction value
Shares: +553,703
Change %
Price
Shares after: 553,703
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F7, F8

PCSC transaction

Common Stock

Award

Transaction value
Shares: +553,703
Change %
Price
Shares after: 553,703
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F7, F8

PCSC transaction

Common Stock

Award

Transaction value
Shares: +553,703
Change %
Price
Shares after: 553,703
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F7, F8

PCSC transaction

Common Stock

Award

Transaction value
Shares: +553,703
Change %
Price
Shares after: 553,703
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F7, F8

PCSC transaction

Common Stock

Award

Transaction value
Shares: +553,703
Change %
Price
Shares after: 553,703
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F7, F8

PCSC transaction

Common Stock

Award

Transaction value
Shares: +553,703
Change %
Price
Shares after: 553,703
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F7, F8

PCSC transaction

Common Stock

Award

Transaction value
Shares: +553,703
Change %
Price
Shares after: 553,703
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F7, F8

PCSC transaction

Common Stock

Award

Transaction value
Shares: +908,103
Change %
Price
Shares after: 908,103
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F9, F10

PCSC transaction

Common Stock

Award

Transaction value
Shares: +908,103
Change %
Price
Shares after: 908,103
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F9, F10

PCSC transaction

Common Stock

Award

Transaction value
Shares: +908,103
Change %
Price
Shares after: 908,103
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F9, F10

PCSC transaction

Common Stock

Award

Transaction value
Shares: +908,103
Change %
Price
Shares after: 908,103
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F9, F10

PCSC transaction

Common Stock

Award

Transaction value
Shares: +908,103
Change %
Price
Shares after: 908,103
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F9, F10

PCSC transaction

Common Stock

Award

Transaction value
Shares: +908,103
Change %
Price
Shares after: 908,103
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F9, F10

PCSC transaction

Common Stock

Award

Transaction value
Shares: +908,103
Change %
Price
Shares after: 908,103
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F9, F10

PCSC transaction

Common Stock

Award

Transaction value
Shares: +367,427
Change %
Price
Shares after: 367,427
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F11, F12

PCSC transaction

Common Stock

Award

Transaction value
Shares: +367,427
Change %
Price
Shares after: 367,427
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F11, F12

PCSC transaction

Common Stock

Award

Transaction value
Shares: +367,427
Change %
Price
Shares after: 367,427
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F11, F12

PCSC transaction

Common Stock

Award

Transaction value
Shares: +367,427
Change %
Price
Shares after: 367,427
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F11, F12

PCSC transaction

Common Stock

Award

Transaction value
Shares: +367,427
Change %
Price
Shares after: 367,427
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F11, F12

PCSC transaction

Common Stock

Award

Transaction value
Shares: +367,427
Change %
Price
Shares after: 367,427
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F11, F12

PCSC transaction

Common Stock

Award

Transaction value
Shares: +367,427
Change %
Price
Shares after: 367,427
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F1, F3, F11, F12

PCSC transaction

Common Stock

Award

Transaction value
Shares: +4,918,411
Change %: +67%
Price: $10.00^*
Shares after: 12,230,122
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F3, F4

PCSC transaction

Common Stock

Award

Transaction value
Shares: +4,918,411
Change %: +67%
Price: $10.00^*
Shares after: 12,230,122
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F3, F4

PCSC transaction

Common Stock

Award

Transaction value
Shares: +4,918,411
Change %: +67%
Price: $10.00^*
Shares after: 12,230,122
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F3, F4

PCSC transaction

Common Stock

Award

Transaction value
Shares: +4,918,411
Change %: +67%
Price: $10.00^*
Shares after: 12,230,122
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F3, F4

PCSC transaction

Common Stock

Award

Transaction value
Shares: +4,918,411
Change %: +67%
Price: $10.00^*
Shares after: 12,230,122
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F3, F4

PCSC transaction

Common Stock

Award

Transaction value
Shares: +4,918,411
Change %: +67%
Price: $10.00^*
Shares after: 12,230,122
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F3, F4

PCSC transaction

Common Stock

Award

Transaction value
Shares: +4,918,411
Change %: +67%
Price: $10.00^*
Shares after: 12,230,122
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F3, F4

PCSC transaction

Common Stock

Award

Transaction value
Shares: +336,965
Change %: +37%
Price: $10.00^*
Shares after: 1,245,068
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F3, F10

PCSC transaction

Common Stock

Award

Transaction value
Shares: +336,965
Change %: +37%
Price: $10.00^*
Shares after: 1,245,068
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F3, F10

PCSC transaction

Common Stock

Award

Transaction value
Shares: +336,965
Change %: +37%
Price: $10.00^*
Shares after: 1,245,068
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F3, F10

PCSC transaction

Common Stock

Award

Transaction value
Shares: +336,965
Change %: +37%
Price: $10.00^*
Shares after: 1,245,068
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F3, F10

PCSC transaction

Common Stock

Award

Transaction value
Shares: +336,965
Change %: +37%
Price: $10.00^*
Shares after: 1,245,068
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F3, F10

PCSC transaction

Common Stock

Award

Transaction value
Shares: +336,965
Change %: +37%
Price: $10.00^*
Shares after: 1,245,068
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F3, F10

PCSC transaction

Common Stock

Award

Transaction value
Shares: +336,965
Change %: +37%
Price: $10.00^*
Shares after: 1,245,068
Date: 20 Jul 2026
Ownership: See footnotes
Footnotes: F3, F10

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 12 footnotes

Footnote F1

Received on July 20, 2026 pursuant to the Business Combination Agreement, dated December 5, 2025 and amended on July 20, 2026 by and among the Issuer, StarNet Merger Sub I, Corp., a wholly-owned subsidiary of the Issuer, StarNet Merger Sub II, LLC, a wholly-owned subsidiary of the Issuer, and Freenome Holdings, Inc. ("Old Freenome") (the "Business Combination").

Footnote F2

Received in the Business Combination in exchange for 4,886,446 shares of Series B Preferred Stock, 4,111,335 shares of Series C Preferred Stock, 4,093,925 shares of Series D Preferred Stock and 10,103,180 shares of Series F Preferred Stock of Old Freenome.

Footnote F3

RA Capital Management, L.P. (the "Adviser") is the investment manager for RA Capital Healthcare Fund, L.P. (the "Fund"), RA Capital Nexus Fund, L.P. (the "Nexus Fund"), RA Capital Nexus Fund II, L.P. (the "Nexus Fund II"), RA Capital Nexus Fund III, L.P. (the "Nexus Fund III"), and a separately managed account (the "Account"). The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. Each of the Adviser, the Adviser GP, the Fund, the Nexus Fund, the Nexus Fund II, the Nexus Fund III, Dr. Kolchinsky and Mr. Shah disclaims beneficial ownership of any of the reported securities, except to the extent of its or his respective pecuniary interest therein.

Footnote F4

Held directly by the Fund.

Footnote F5

Received in the Business Combination in exchange for 1,920,093 shares of Series B Preferred Stock and 1,512,104 shares of Series C Preferred Stock of Old Freenome.

Footnote F6

Held directly by the Nexus Fund.

Footnote F7

Received in the Business Combination in exchange for 1,754,539 shares of Series D Preferred Stock and 202,739 shares of Series F Preferred Stock of Old Freenome.

Footnote F8

Held directly by Nexus Fund II.

Footnote F9

Received in the Business Combination in exchange for 3,210,040 shares of Series F Preferred Stock of Old Freenome.

Footnote F10

Held directly by Nexus Fund III.

Footnote F11

Received in the Business Combination in exchange for 873,834 shares of Series B Preferred Stock and 424,978 shares of Series C Preferred Stock of Old Freenome.

Footnote F12

Held directly by the Account.

SEC remarks

Dr. Peter Kolchinsky, a Managing Partner of the Adviser, serves on the Issuer's board of directors.