Seth Loring Harrison - 16 Jul 2026 Form 4 Insider Report for Stoke Therapeutics, Inc. (STOK)

Reporting relationship: Director
Issuer ticker: STOK
Reported as of: 16 Jul 2026
Net transaction value: $0
SEC form: 4
Accepted by SEC: 17 Jul 2026, 16:37:22 UTC
Prior SEC filing: 05 Jun 2026
Source filing: View source filing
Reporting owner signature: /s/ Jonathan Allan, Attorney-in-Fact

Key filing fact

Seth Loring Harrison filed Form 4 for Stoke Therapeutics, Inc. (STOK) on 17 Jul 2026.

Key facts

This page summarizes Seth Loring Harrison's Form 4 filing for Stoke Therapeutics, Inc. (STOK).
16 reported transactions and 16 derivative rows are listed below.
Accepted by SEC: 17 Jul 2026, 16:37.

Change

Previous filing in this sequence was filed on 05 Jun 2026.
Current net transaction value: $0.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001404955 Primary reporting owner

Harrison Seth Loring

Relationship: Director
Address: C/O STOKE THERAPEUTICS, INC., 45 WIGGINS AVENUE, BEDFORD
Signature: /s/ Jonathan Allan, Attorney-in-Fact
Signature date: 17 Jul 2026

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

STOK transaction Derivative

Stock Option (Right to Buy)

Gift

Transaction value
Shares: -29,555
Change %: -100%
Price: $0.000000^*
Shares after: 0
Date: 16 Jul 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 29,555
Exercise price: $28.80
Footnotes: F1, F2

STOK transaction Derivative

Stock Option (Right to Buy)

Gift

Transaction value
Shares: +29,555
Change %
Price: $0.000000^*
Shares after: 29,555
Date: 16 Jul 2026
Ownership: By Trust
Underlying class: Common Stock
Underlying amount: 29,555
Exercise price: $28.80
Footnotes: F1, F2, F3

STOK transaction Derivative

Stock Option (Right to Buy)

Gift

Transaction value
Shares: -14,777
Change %: -100%
Price: $0.000000^*
Shares after: 0
Date: 16 Jul 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 14,777
Exercise price: $26.53
Footnotes: F1, F4

STOK transaction Derivative

Stock Option (Right to Buy)

Gift

Transaction value
Shares: +14,777
Change %
Price: $0.000000^*
Shares after: 14,777
Date: 16 Jul 2026
Ownership: By Trust
Underlying class: Common Stock
Underlying amount: 14,777
Exercise price: $26.53
Footnotes: F1, F3, F4

STOK transaction Derivative

Stock Option (Right to Buy)

Gift

Transaction value
Shares: -11,650
Change %: -100%
Price: $0.000000^*
Shares after: 0
Date: 16 Jul 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 11,650
Exercise price: $40.37
Footnotes: F1, F5

STOK transaction Derivative

Stock Option (Right to Buy)

Gift

Transaction value
Shares: +11,650
Change %
Price: $0.000000^*
Shares after: 11,650
Date: 16 Jul 2026
Ownership: By Trust
Underlying class: Common Stock
Underlying amount: 11,650
Exercise price: $40.37
Footnotes: F1, F3, F5

STOK transaction Derivative

Stock Option (Right to Buy)

Gift

Transaction value
Shares: -21,000
Change %: -100%
Price: $0.000000^*
Shares after: 0
Date: 16 Jul 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 21,000
Exercise price: $12.96
Footnotes: F1, F6

STOK transaction Derivative

Stock Option (Right to Buy)

Gift

Transaction value
Shares: +21,000
Change %
Price: $0.000000^*
Shares after: 21,000
Date: 16 Jul 2026
Ownership: By Trust
Underlying class: Common Stock
Underlying amount: 21,000
Exercise price: $12.96
Footnotes: F1, F3, F6

STOK transaction Derivative

Stock Option (Right to Buy)

Gift

Transaction value
Shares: -19,441
Change %: -100%
Price: $0.000000^*
Shares after: 0
Date: 16 Jul 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 19,441
Exercise price: $12.46
Footnotes: F1, F7

STOK transaction Derivative

Stock Option (Right to Buy)

Gift

Transaction value
Shares: +19,441
Change %
Price: $0.000000^*
Shares after: 19,441
Date: 16 Jul 2026
Ownership: By Trust
Underlying class: Common Stock
Underlying amount: 19,441
Exercise price: $12.46
Footnotes: F1, F3, F7

STOK transaction Derivative

Stock Option (Right to Buy)

Gift

Transaction value
Shares: -7,639
Change %: -100%
Price: $0.000000^*
Shares after: 0
Date: 16 Jul 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 7,639
Exercise price: $16.41
Footnotes: F1, F8

STOK transaction Derivative

Stock Option (Right to Buy)

Gift

Transaction value
Shares: +7,639
Change %
Price: $0.000000^*
Shares after: 7,639
Date: 16 Jul 2026
Ownership: By Trust
Underlying class: Common Stock
Underlying amount: 7,639
Exercise price: $16.41
Footnotes: F1, F3, F8

STOK transaction Derivative

Stock Option (Right to Buy)

Gift

Transaction value
Shares: -29,747
Change %: -100%
Price: $0.000000^*
Shares after: 0
Date: 16 Jul 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 29,747
Exercise price: $10.90
Footnotes: F1, F9

STOK transaction Derivative

Stock Option (Right to Buy)

Gift

Transaction value
Shares: +29,747
Change %
Price: $0.000000^*
Shares after: 29,747
Date: 16 Jul 2026
Ownership: By Trust
Underlying class: Common Stock
Underlying amount: 29,747
Exercise price: $10.90
Footnotes: F1, F3, F9

STOK transaction Derivative

Stock Option (Right to Buy)

Gift

Transaction value
Shares: -17,786
Change %: -100%
Price: $0.000000^*
Shares after: 0
Date: 16 Jul 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 17,786
Exercise price: $29.46
Footnotes: F1, F10

STOK transaction Derivative

Stock Option (Right to Buy)

Gift

Transaction value
Shares: +17,786
Change %
Price: $0.000000^*
Shares after: 17,786
Date: 16 Jul 2026
Ownership: By Trust
Underlying class: Common Stock
Underlying amount: 17,786
Exercise price: $29.46
Footnotes: F1, F3, F10

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 10 footnotes

Footnote F1

The reported transaction represents a gift, for no consideration, of shares of the Issuer's Common Stock, which is exempt from short-swing profit liability pursuant to Rule 16b-5 under the Exchange Act of 1934, as amended.

Footnote F2

This option is fully vested and exercisable. Pursuant to the grant agreement between the Issuer and the reporting person, the award became fully vested on March 21, 2022.

Footnote F3

The securities are directly held by the East Pillar 2026 Irrevocable Trust (the "Trust"). The reporting person is a member of the board of managers of the Trust's trustee and may be deemed to exercise voting discretion, as well as shared investment discretion, in such capacity. The reporting person and certain of his immediate family members are beneficiaries of the Trust.

Footnote F4

This option is fully vested and exercisable. Pursuant to the grant agreement between the Issuer and the reporting person, the award became fully vested on June 3, 2021.

Footnote F5

This option is fully vested and exercisable. Pursuant to the grant agreement between the Issuer and the reporting person, the award became fully vested on June 8, 2022.

Footnote F6

This option is fully vested and exercisable. Pursuant to the grant agreement between the Issuer and the reporting person, the award became fully vested on June 7, 2023.

Footnote F7

This option is fully vested and exercisable. Pursuant to the grant agreement between the Issuer and the reporting person, the award became fully vested on June 13, 2024.

Footnote F8

This option is fully vested and exercisable. Pursuant to the grant agreement between the Issuer and the reporting person, the award became fully vested on June 3, 2025.

Footnote F9

This option is fully vested and exercisable. Pursuant to the grant agreement between the Issuer and the reporting person, the award became fully vested on June 3, 2026.

Footnote F10

The option shall vest in full on the earlier of: (i) June 3, 2027 or (ii) the date of the Issuer's next annual meeting of its stockholders, subject to the reporting person's continued service to the Issuer on the vesting date.