Brenda Hefti - 15 May 2026 Form 4 Insider Report for EXELIXIS, INC. (EXEL)

Reporting relationship: SVP and General Counsel
Issuer ticker: EXEL
Reported as of: 15 May 2026
Net transaction value: -$332,641
SEC form: 4
Accepted by SEC: 19 May 2026, 18:58:31 UTC
Prior SEC filing: 02 Mar 2026
Source filing: View source filing
Reporting owner signature: /s/ Nina Ayer, Attorney in Fact

Key filing fact

Brenda Hefti filed Form 4 for EXELIXIS, INC. (EXEL) on 19 May 2026.

Key facts

This page summarizes Brenda Hefti's Form 4 filing for EXELIXIS, INC. (EXEL).
2 reported transactions and 0 derivative rows are listed below.
Accepted by SEC: 19 May 2026, 18:58.

Change

Previous filing in this sequence was filed on 02 Mar 2026.
Current net transaction value: -$332,641.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0002097579 Primary reporting owner

Hefti Brenda

Relationship: SVP and General Counsel
Address: 1851 HARBOR BAY PARKWAY, ALAMEDA
Signature: /s/ Nina Ayer, Attorney in Fact
Signature date: 19 May 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

EXEL transaction

Common Stock

Tax liability

Transaction value
Shares: -6,411
Change %: -5.4%
Price: $51.10^*
Shares after: 113,387
Date: 15 May 2026
Ownership: Direct
Footnotes: F1, F2

EXEL transaction

Common Stock

Sale

Transaction value: $332,641
Shares: -6,625
Change %: -5.8%
Price: $50.21
Shares after: 106,762
Date: 18 May 2026
Ownership: Direct
Footnotes: F2, F3, F4

EXEL holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 5,527
Date: 15 May 2026
Ownership: By 401(k)
Footnotes: F5

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Rule 10b5-1 trading plan

These transactions were reported as open-market trades under a Rule 10b5-1 plan. The plan lets an insider set trading instructions in advance, which can reduce the risk of trading while in possession of material nonpublic information.

Original filing language: transaction made pursuant to a contract, instruction, or written plan intended to satisfy Rule 10b5-1(c).

Explanation of responses 5 footnotes

Footnote F1

Shares withheld by Exelixis, Inc. to satisfy taxes payable in connection with the vesting of restricted stock units ("RSUs") awarded on March 4, 2022, February 29, 2024, and February 26, 2025.

Footnote F2

Includes 106,039 shares of Exelixis, Inc. common stock ("Common Stock") that will be issued to the Reporting Person upon vesting of RSUs, the performance-based restricted stock unit award granted to the Reporting Person on March 31, 2025 ("One-Time Award PSUs") and 167 shares of Common Stock acquired on April 30, 2026, pursuant to the Exelixis, Inc. 2000 Employee Stock Purchase Plan. Each RSU is the economic equivalent of one share of Common Stock and each One-Time Award PSU represents a contingent right to receive one share of Common Stock.

Footnote F3

The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 19, 2025.

Footnote F4

Represents the weighted average sales price. The shares of Common Stock were sold in multiple transactions at prices ranging from $49.84 to $50.51. Reporting Person undertakes to provide Exelixis, Inc., any security holder of Exelixis, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote 4 to this Form 4.

Footnote F5

Represents shares of Common Stock under the Exelixis, Inc. 401(k) Plan, pursuant to a plan statement dated as of May 14, 2026.