Patricia C. Hirano - 18 May 2026 Form 4 Insider Report for SOLENO THERAPEUTICS INC (SLNO)

Reporting relationship: Officer title: Senior Vice President, Regulatory Affairs
Issuer ticker: SLNO
Reported as of: 18 May 2026
Net transaction value: $0
SEC form: 4
Accepted by SEC: 18 May 2026, 16:36:42 UTC
Prior SEC filing: 23 Jan 2026
Source filing: View source filing
Reporting owner signature: /s/ Anish Bhatnagar, Attorney-in-Fact

Key filing fact

Patricia C. Hirano filed Form 4 for SOLENO THERAPEUTICS INC (SLNO) on 18 May 2026.

Key facts

This page summarizes Patricia C. Hirano's Form 4 filing for SOLENO THERAPEUTICS INC (SLNO).
10 reported transactions and 9 derivative rows are listed below.
Accepted by SEC: 18 May 2026, 16:36.

Change

Previous filing in this sequence was filed on 23 Jan 2026.
Current net transaction value: $0.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001766042 Primary reporting owner

Hirano Patricia C

Relationship: Officer title: Senior Vice President, Regulatory Affairs
Address: 100 MARINE PARKWAY, SUITE 400, REDWOOD CITY
Signature: /s/ Anish Bhatnagar, Attorney-in-Fact
Signature date: 18 May 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

SLNO transaction

Common Stock

Disposed to Issuer

Transaction value
Shares: -22,702
Change %: -100%
Price
Shares after: 0
Date: 18 May 2026
Ownership: Direct
Footnotes: F1, F2

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

SLNO transaction Derivative

Employee Stock Option (Right to buy)

Disposed to Issuer

Transaction value
Shares: -2,333
Change %: -100%
Price
Shares after: 0
Date: 18 May 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 2,333
Exercise price: $51.15
Footnotes: F3

SLNO transaction Derivative

Employee Stock Option (Right to buy)

Disposed to Issuer

Transaction value
Shares: -18,842
Change %: -100%
Price
Shares after: 0
Date: 18 May 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 18,842
Exercise price: $33.60
Footnotes: F3

SLNO transaction Derivative

Employee Stock Option (Right to buy)

Disposed to Issuer

Transaction value
Shares: -2,445
Change %: -100%
Price
Shares after: 0
Date: 18 May 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 2,445
Exercise price: $5.10
Footnotes: F3

SLNO transaction Derivative

Employee Stock Option (Right to buy)

Disposed to Issuer

Transaction value
Shares: -11,667
Change %: -100%
Price
Shares after: 0
Date: 18 May 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 11,667
Exercise price: $2.41
Footnotes: F3

SLNO transaction Derivative

Employee Stock Option (Right to buy)

Disposed to Issuer

Transaction value
Shares: -49,262
Change %: -100%
Price
Shares after: 0
Date: 18 May 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 49,262
Exercise price: $5.25
Footnotes: F3

SLNO transaction Derivative

Employee Stock Option (Right to buy)

Disposed to Issuer

Transaction value
Shares: -16,000
Change %: -100%
Price
Shares after: 0
Date: 18 May 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 16,000
Exercise price: $36.70
Footnotes: F3

SLNO transaction Derivative

Employee Stock Option (Right to buy)

Disposed to Issuer

Transaction value
Shares: -13,800
Change %: -100%
Price
Shares after: 0
Date: 18 May 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 13,800
Exercise price: $49.17
Footnotes: F3

SLNO transaction Derivative

Employee Stock Option (Right to buy)

Disposed to Issuer

Transaction value
Shares: -11,900
Change %: -100%
Price
Shares after: 0
Date: 18 May 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 11,900
Exercise price: $43.65
Footnotes: F3

SLNO transaction Derivative

Warrant (Right to buy)

Disposed to Issuer

Transaction value
Shares: -1,333
Change %: -100%
Price
Shares after: 0
Date: 18 May 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 1,333
Exercise price: $4.50
Footnotes: F4

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Section 16 status

Patricia C. Hirano is no longer subject to Section 16 filing requirements. Form 4 or Form 5 obligations may still apply in specific circumstances.

Explanation of responses 4 footnotes

Footnote F1

Certain of these shares are represented by previously reported restricted stock units ("RSUs"). Pursuant to the Agreement and Plan of Merger, dated as of April 5, 2026, by and among Soleno Therapeutics, Inc. (the "Company"), Neocrine Biosciences, Inc. ("Parent") and Sigma Merger Sub, Inc. ("Merger Sub"), on May 18, 2026, Merger Sub merged with and into the Company (the "Merger"), with the Company continuing as the surviving corporation and a wholly owned subsidiary of Parent. In connection with the Merger, each issued and outstanding vested and unvested RSU was cancelled and converted into the right to receive an amount equal to $53.00 in cash (the "Merger Consideration").

Footnote F2

In connection with the Merger, each issued and outstanding share of the Company's Common Stock was cancelled and converted into the right to receive an amount in cash equal to the Merger Consideration.

Footnote F3

At the effective time of the Merger, this option was cancelled in exchange for a cash payment equal to (x) the difference between the Merger Consideration and the per share exercise price of the option, multiplied by (y) the number of shares covered by the option as of immediately prior to such cancellation.

Footnote F4

At the effective time of the Merger, this warrant was cancelled in exchange for a cash payment equal to (i) the product of 1,333 warrant shares multiplied by the Merger Consideration minus (ii) the $4.50 per share exercise price of the warrant.

SEC remarks

Officer title: Senior Vice President, Regulatory Affairs