SR ONE CAPITAL MANAGEMENT, LLC - 11 May 2026 Form 4 Insider Report for Odyssey Therapeutics, Inc. (ODTX)

Source evidence Original filing metadata and source links for verification. 4 source fields
SEC form
4
Accepted by SEC
11 May 2026, 21:11:42 UTC
Prior SEC filing
07 May 2026
Source filing
View source filing
Reporting owner 1 detail
Reporting owner signature
/s/ Sasha Keough, attorney-in-fact for SR One Capital Management, LLC

Key filing fact

SR ONE CAPITAL MANAGEMENT, LLC filed Form 4 for Odyssey Therapeutics, Inc. (ODTX) on 11 May 2026.

Key facts

  • This page summarizes SR ONE CAPITAL MANAGEMENT, LLC's Form 4 filing for Odyssey Therapeutics, Inc. (ODTX).
  • 36 reported transactions and 30 derivative rows are listed below.
  • Accepted by SEC: 11 May 2026, 21:11.

Change

  • Previous filing in this sequence was filed on 07 May 2026.
  • Current net transaction value: $0.

Research use

  • This tells you what this filing adds before you inspect full transaction and derivative tables.
  • You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (2)

CIK 0001853723 Primary reporting owner

SR ONE CAPITAL MANAGEMENT, LLC

Relationship
10%+ Owner
Address
929 MAIN STREET, SUITE 200, REDWOOD CITY
Signature
/s/ Sasha Keough, attorney-in-fact for SR One Capital Management, LLC
Signature date
11 May 2026
CIK 0001595117

George Simeon

Relationship
10%+ Owner
Address
929 MAIN STREET, SUITE 200, REDWOOD CITY
Signature
/s/ Sasha Keough, attorney-in-fact for Simeon George
Signature date
11 May 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+474,048
Change %
Price
Shares after
474,048
Date
11 May 2026
Ownership
See Note 2
Footnotes
F1, F2
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+474,048
Change %
Price
Shares after
474,048
Date
11 May 2026
Ownership
See Note 2
Footnotes
F1, F2
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+139,366
Change %
+29%
Price
Shares after
613,414
Date
11 May 2026
Ownership
See Note 2
Footnotes
F2, F3
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+139,366
Change %
+29%
Price
Shares after
613,414
Date
11 May 2026
Ownership
See Note 2
Footnotes
F2, F3
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+59,692
Change %
+9.7%
Price
Shares after
673,106
Date
11 May 2026
Ownership
See Note 2
Footnotes
F2, F4
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+59,692
Change %
+9.7%
Price
Shares after
673,106
Date
11 May 2026
Ownership
See Note 2
Footnotes
F2, F4
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+61,762
Change %
+9.2%
Price
Shares after
734,868
Date
11 May 2026
Ownership
See Note 2
Footnotes
F2, F5
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+61,762
Change %
+9.2%
Price
Shares after
734,868
Date
11 May 2026
Ownership
See Note 2
Footnotes
F2, F5
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+683,817
Change %
+93%
Price
Shares after
1,418,685
Date
11 May 2026
Ownership
See Note 2
Footnotes
F2, F6
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+683,817
Change %
+93%
Price
Shares after
1,418,685
Date
11 May 2026
Ownership
See Note 2
Footnotes
F2, F6
ODTX transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares
+191,541
Change %
+14%
Price
Shares after
1,610,226
Date
11 May 2026
Ownership
See Note 2
Footnotes
F2, F7
ODTX transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares
+191,541
Change %
+14%
Price
Shares after
1,610,226
Date
11 May 2026
Ownership
See Note 2
Footnotes
F2, F7
ODTX transaction

Common Stock

Sale

Transaction value
Shares
-1,065
Change %
-0.07%
Price
$18.00*
Shares after
1,609,161
Date
11 May 2026
Ownership
See Note 2
Footnotes
F2, F7, F8
ODTX transaction

Common Stock

Sale

Transaction value
Shares
-1,065
Change %
-0.07%
Price
$18.00*
Shares after
1,609,161
Date
11 May 2026
Ownership
See Note 2
Footnotes
F2, F7, F8
ODTX transaction

Common Stock

Purchase

Transaction value
Shares
+222,222
Change %
+14%
Price
$18.00*
Shares after
1,831,383
Date
11 May 2026
Ownership
See Note 2
Footnotes
F2
ODTX transaction

Common Stock

Purchase

Transaction value
Shares
+222,222
Change %
+14%
Price
$18.00*
Shares after
1,831,383
Date
11 May 2026
Ownership
See Note 2
Footnotes
F2
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+118,512
Change %
Price
Shares after
118,512
Date
11 May 2026
Ownership
See Note 9
Footnotes
F1, F9
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+118,512
Change %
Price
Shares after
118,512
Date
11 May 2026
Ownership
See Note 9
Footnotes
F1, F9
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+255,823
Change %
+216%
Price
Shares after
374,335
Date
11 May 2026
Ownership
See Note 9
Footnotes
F4, F9
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+255,823
Change %
+216%
Price
Shares after
374,335
Date
11 May 2026
Ownership
See Note 9
Footnotes
F4, F9
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+204,658
Change %
Price
Shares after
204,658
Date
11 May 2026
Ownership
See Note 10
Footnotes
F4, F10
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+204,658
Change %
Price
Shares after
204,658
Date
11 May 2026
Ownership
See Note 10
Footnotes
F4, F10
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+20,582
Change %
+10%
Price
Shares after
225,240
Date
11 May 2026
Ownership
See Note 10
Footnotes
F5, F10
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+20,582
Change %
+10%
Price
Shares after
225,240
Date
11 May 2026
Ownership
See Note 10
Footnotes
F5, F10
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+166,168
Change %
+74%
Price
Shares after
391,408
Date
11 May 2026
Ownership
See Note 10
Footnotes
F6, F10
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+166,168
Change %
+74%
Price
Shares after
391,408
Date
11 May 2026
Ownership
See Note 10
Footnotes
F6, F10
ODTX transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares
+49,850
Change %
+13%
Price
Shares after
441,258
Date
11 May 2026
Ownership
See Note 10
Footnotes
F7, F10
ODTX transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares
+49,850
Change %
+13%
Price
Shares after
441,258
Date
11 May 2026
Ownership
See Note 10
Footnotes
F7, F10
ODTX transaction

Common Stock

Sale

Transaction value
Shares
-277
Change %
-0.06%
Price
$18.00*
Shares after
440,981
Date
11 May 2026
Ownership
See Note 10
Footnotes
F7, F10, F11
ODTX transaction

Common Stock

Sale

Transaction value
Shares
-277
Change %
-0.06%
Price
$18.00*
Shares after
440,981
Date
11 May 2026
Ownership
See Note 10
Footnotes
F7, F10, F11
ODTX transaction

Common Stock

Purchase

Transaction value
Shares
+133,333
Change %
+30%
Price
$18.00*
Shares after
574,314
Date
11 May 2026
Ownership
See Note 10
Footnotes
F10
ODTX transaction

Common Stock

Purchase

Transaction value
Shares
+133,333
Change %
+30%
Price
$18.00*
Shares after
574,314
Date
11 May 2026
Ownership
See Note 10
Footnotes
F10
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+463,106
Change %
Price
Shares after
463,106
Date
11 May 2026
Ownership
See Note 12
Footnotes
F5, F12
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+463,106
Change %
Price
Shares after
463,106
Date
11 May 2026
Ownership
See Note 12
Footnotes
F5, F12
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+273,527
Change %
+59%
Price
Shares after
736,633
Date
11 May 2026
Ownership
See Note 12
Footnotes
F6, F12
ODTX transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+273,527
Change %
+59%
Price
Shares after
736,633
Date
11 May 2026
Ownership
See Note 12
Footnotes
F6, F12
ODTX transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares
+78,656
Change %
+11%
Price
Shares after
815,289
Date
11 May 2026
Ownership
See Note 12
Footnotes
F7, F12
ODTX transaction

Common Stock

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares
+78,656
Change %
+11%
Price
Shares after
815,289
Date
11 May 2026
Ownership
See Note 12
Footnotes
F7, F12
ODTX transaction

Common Stock

Sale

Transaction value
Shares
-438
Change %
-0.05%
Price
$18.00*
Shares after
814,851
Date
11 May 2026
Ownership
See Note 12
Footnotes
F7, F12, F13
ODTX transaction

Common Stock

Sale

Transaction value
Shares
-438
Change %
-0.05%
Price
$18.00*
Shares after
814,851
Date
11 May 2026
Ownership
See Note 12
Footnotes
F7, F12, F13
ODTX transaction

Common Stock

Purchase

Transaction value
Shares
+200,000
Change %
+25%
Price
$18.00*
Shares after
1,014,851
Date
11 May 2026
Ownership
See Note 12
Footnotes
F12
ODTX transaction

Common Stock

Purchase

Transaction value
Shares
+200,000
Change %
+25%
Price
$18.00*
Shares after
1,014,851
Date
11 May 2026
Ownership
See Note 12
Footnotes
F12

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

ODTX transaction Derivative

Series A Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-4,606,320
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 2
Underlying class
Common Stock
Underlying amount
474,048
Exercise price
Footnotes
F1, F2
ODTX transaction Derivative

Series A Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-4,606,320
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 2
Underlying class
Common Stock
Underlying amount
474,048
Exercise price
Footnotes
F1, F2
ODTX transaction Derivative

Series A-2 Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-1,299,842
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 2
Underlying class
Common Stock
Underlying amount
139,366
Exercise price
Footnotes
F2, F3
ODTX transaction Derivative

Series A-2 Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-1,299,842
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 2
Underlying class
Common Stock
Underlying amount
139,366
Exercise price
Footnotes
F2, F3
ODTX transaction Derivative

Series B Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-544,162
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 2
Underlying class
Common Stock
Underlying amount
59,692
Exercise price
Footnotes
F2, F4
ODTX transaction Derivative

Series B Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-544,162
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 2
Underlying class
Common Stock
Underlying amount
59,692
Exercise price
Footnotes
F2, F4
ODTX transaction Derivative

Series C Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-600,142
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 2
Underlying class
Common Stock
Underlying amount
61,762
Exercise price
Footnotes
F2, F5
ODTX transaction Derivative

Series C Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-600,142
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 2
Underlying class
Common Stock
Underlying amount
61,762
Exercise price
Footnotes
F2, F5
ODTX transaction Derivative

Series D Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-6,644,650
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 2
Underlying class
Common Stock
Underlying amount
683,817
Exercise price
Footnotes
F2, F6
ODTX transaction Derivative

Series D Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-6,644,650
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 2
Underlying class
Common Stock
Underlying amount
683,817
Exercise price
Footnotes
F2, F6
ODTX transaction Derivative

Series D Warrants (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares
-1,861,211
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 2
Underlying class
Common Stock
Underlying amount
191,541
Exercise price
$0.1000
Footnotes
F2, F7
ODTX transaction Derivative

Series D Warrants (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares
-1,861,211
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 2
Underlying class
Common Stock
Underlying amount
191,541
Exercise price
$0.1000
Footnotes
F2, F7
ODTX transaction Derivative

Series A Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-1,151,580
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 9
Underlying class
Common Stock
Underlying amount
118,512
Exercise price
Footnotes
F1, F9
ODTX transaction Derivative

Series A Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-1,151,580
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 9
Underlying class
Common Stock
Underlying amount
118,512
Exercise price
Footnotes
F1, F9
ODTX transaction Derivative

Series B Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-2,374,981
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 9
Underlying class
Common Stock
Underlying amount
255,823
Exercise price
Footnotes
F4, F9
ODTX transaction Derivative

Series B Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-2,374,981
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 9
Underlying class
Common Stock
Underlying amount
255,823
Exercise price
Footnotes
F4, F9
ODTX transaction Derivative

Series B Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-1,899,984
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 10
Underlying class
Common Stock
Underlying amount
204,658
Exercise price
Footnotes
F4, F10
ODTX transaction Derivative

Series B Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-1,899,984
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 10
Underlying class
Common Stock
Underlying amount
204,658
Exercise price
Footnotes
F4, F10
ODTX transaction Derivative

Series C Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-200,000
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 10
Underlying class
Common Stock
Underlying amount
20,582
Exercise price
Footnotes
F5, F10
ODTX transaction Derivative

Series C Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-200,000
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 10
Underlying class
Common Stock
Underlying amount
20,582
Exercise price
Footnotes
F5, F10
ODTX transaction Derivative

Series D Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-1,614,650
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 10
Underlying class
Common Stock
Underlying amount
166,168
Exercise price
Footnotes
F6, F10
ODTX transaction Derivative

Series D Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-1,614,650
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 10
Underlying class
Common Stock
Underlying amount
166,168
Exercise price
Footnotes
F6, F10
ODTX transaction Derivative

Series D Warrants (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares
-484,395
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 10
Underlying class
Common Stock
Underlying amount
49,850
Exercise price
$0.1000
Footnotes
F7, F10
ODTX transaction Derivative

Series D Warrants (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares
-484,395
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 10
Underlying class
Common Stock
Underlying amount
49,850
Exercise price
$0.1000
Footnotes
F7, F10
ODTX transaction Derivative

Series C Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-4,500,000
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 12
Underlying class
Common Stock
Underlying amount
463,106
Exercise price
Footnotes
F5, F12
ODTX transaction Derivative

Series C Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-4,500,000
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 12
Underlying class
Common Stock
Underlying amount
463,106
Exercise price
Footnotes
F5, F12
ODTX transaction Derivative

Series D Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-2,657,860
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 12
Underlying class
Common Stock
Underlying amount
273,527
Exercise price
Footnotes
F6, F12
ODTX transaction Derivative

Series D Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-2,657,860
Change %
-100%
Price
Shares after
0
Date
11 May 2026
Ownership
See Note 12
Underlying class
Common Stock
Underlying amount
273,527
Exercise price
Footnotes
F6, F12
ODTX transaction Derivative

Series D Warrants (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares
-764,312
Change %
-100%
Price
$0.000000*
Shares after
0
Date
11 May 2026
Ownership
See Note 12
Underlying class
Common Stock
Underlying amount
78,656
Exercise price
$0.1000
Footnotes
F7, F12
ODTX transaction Derivative

Series D Warrants (Right to Buy)

Exercise of in-the-money or at-the-money derivative security

Transaction value
Shares
-764,312
Change %
-100%
Price
$0.000000*
Shares after
0
Date
11 May 2026
Ownership
See Note 12
Underlying class
Common Stock
Underlying amount
78,656
Exercise price
$0.1000
Footnotes
F7, F12
* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Section 16 status

SR ONE CAPITAL MANAGEMENT, LLC is no longer subject to Section 16 filing requirements. Form 4 or Form 5 obligations may still apply in specific circumstances.

Explanation of responses 13 footnotes

Footnote F1

The Series A Preferred Stock automatically converted into Common Stock immediately prior to the closing of the Issuer's initial public offering on a 1-for-9.7170 basis for no additional consideration.

Footnote F2

The securities are directly held by SR One Capital Fund I Aggregator, LP ("SR One Fund I Aggregator"). SR One Capital Partners I, LP ("SR One Partners I") is the sole general partner of SR One Fund I Aggregator, and SR One Capital Management, LLC ("SR One Capital Management") is the sole general partner of SR One Partners I. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One Capital Partners I, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.

Footnote F3

The Series A-2 Preferred Stock automatically converted into Common Stock immediately prior to the closing of the Issuer's initial public offering on a 1-for-9.3268 basis for no additional consideration.

Footnote F4

The Series B Preferred Stock automatically converted into Common Stock immediately prior to the closing of the Issuer's initial public offering on a 1-for-9.2837 basis for no additional consideration.

Footnote F5

The Series C Preferred Stock automatically converted into Common Stock immediately prior to the closing of the Issuer's initial public offering on a 1-for-9.7170 basis for no additional consideration.

Footnote F6

The Series D Preferred Stock automatically converted into Common Stock immediately prior to the closing of the Issuer's initial public offering on a 1-for-9.7170 basis for no additional consideration.

Footnote F7

The warrants to purchase shares of common stock were automatically exercised into shares of Common Stock by their terms immediately prior to the closing of the Issuer's initial public offering on a net exercise basis.

Footnote F8

Pursuant to the terms of the warrants, the Issuer withheld 1,065 warrant shares to pay the exercise price in connection with the net exercise.

Footnote F9

The securities are directly held by SR One Co-Invest IV, LLC ("SR One Co-Invest IV"). SR One Co-Invest IV Manager, LLC ("SR One Co-Invest Manager") is the managing member of SR One-Co-Invest IV, and SR One Capital Management is the managing member of SR One Co-Invest Manager. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One Co-Invest Manager, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.

Footnote F10

The securities are directly held by SR One Co-Invest IV-A, LLC ("SR One Co-Invest IV-A"). SR One Co-Invest IV Manager is the managing member of SR One-Co-Invest IV-A, and SR One Capital Management is the managing member of SR One Co-Invest Manager. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One Co-Invest Manager, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.

Footnote F11

Pursuant to the terms of the warrants, the Issuer withheld 277 warrant shares to pay the exercise price in connection with the net exercise.

Footnote F12

The reported securities are held directly by AMZL, LP ("AMZL"). SR One Capital SMA Partners, LP ("SR One SMA Partners") is the general partner of AMZL, and SR One Capital Management is the general partner of SR One SMA Partners. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One SMA Partners, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.

Footnote F13

Pursuant to the terms of the warrants, the Issuer withheld 438 warrant shares to pay the exercise price in connection with the net exercise.

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