Casdin Capital, LLC - 07 May 2026 Form 4 Insider Report for GeneDx Holdings Corp. (WGS)

Reporting relationship: Director, 10%+ Owner
Issuer ticker: WGS
Reported as of: 07 May 2026
Net transaction value: $0
SEC form: 4
Accepted by SEC: 11 May 2026, 20:43:39 UTC
Prior SEC filing: 22 Aug 2025
Next SEC filing: 20 May 2026
Source filing: View source filing
Reporting owner signature: Casdin Capital LLC, By: /s/ Eli Casdin, Managing Member

Key filing fact

Casdin Capital, LLC filed Form 4 for GeneDx Holdings Corp. (WGS) on 11 May 2026.

Key facts

This page summarizes Casdin Capital, LLC's Form 4 filing for GeneDx Holdings Corp. (WGS).
3 reported transactions and 12 derivative rows are listed below.
Accepted by SEC: 11 May 2026, 20:43.

Change

Previous filing in this sequence was filed on 22 Aug 2025.
Current net transaction value: $0.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (4)

CIK 0001534261 Primary reporting owner

Casdin Capital, LLC

Relationship: Director, 10%+ Owner
Address: 1350 AVENUE OF THE AMERICAS, SUITE 2600, NEW YORK
Signature: Casdin Capital LLC, By: /s/ Eli Casdin, Managing Member
Signature date: 11 May 2026

CIK 0001534264

Casdin Eli

Relationship: Director, 10%+ Owner
Address: 1350 AVENUE OF THE AMERICAS, SUITE 2600, NEW YORK
Signature: /s/ Eli Casdin, Eli Casdin
Signature date: 11 May 2026

CIK 0001534265

Casdin Partners Master Fund, L.P.

Relationship: Director, 10%+ Owner
Address: 1350 AVENUE OF THE AMERICAS, SUITE 2600, NEW YORK
Signature: Casdin Partners Master Fund, LP, By: Casdin Partners GP, LLC, its General Partner, By: /s/ Eli Casdin, Managing Member
Signature date: 11 May 2026

CIK 0001534260

Casdin Partners GP, LLC

Relationship: Director, 10%+ Owner
Address: 1350 AVENUE OF THE AMERICAS, SUITE 2600, NEW YORK
Signature: Casdin Partners GP LLC, By: /s/ Eli Casdin, Managing Member, /s/ Eli Casdin, Eli Casdin
Signature date: 11 May 2026

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

WGS transaction Derivative

Cash Settled Swap

Purchase

Transaction value
Shares: +500,000
Change %
Price
Shares after: 500,000
Date: 07 May 2026
Ownership: See Footnote
Underlying class: Class A Common Stock
Underlying amount: 500,000
Exercise price
Footnotes: F1, F2

WGS transaction Derivative

Cash Settled Swap

Purchase

Transaction value
Shares: +500,000
Change %
Price
Shares after: 500,000
Date: 07 May 2026
Ownership: See Footnote
Underlying class: Class A Common Stock
Underlying amount: 500,000
Exercise price
Footnotes: F1, F2

WGS transaction Derivative

Cash Settled Swap

Purchase

Transaction value
Shares: +500,000
Change %
Price
Shares after: 500,000
Date: 07 May 2026
Ownership: See Footnote
Underlying class: Class A Common Stock
Underlying amount: 500,000
Exercise price
Footnotes: F1, F2

WGS transaction Derivative

Cash Settled Swap

Purchase

Transaction value
Shares: +500,000
Change %
Price
Shares after: 500,000
Date: 07 May 2026
Ownership: See Footnote
Underlying class: Class A Common Stock
Underlying amount: 500,000
Exercise price
Footnotes: F1, F2

WGS transaction Derivative

Cash Settled Swap

Purchase

Transaction value
Shares: +300,000
Change %: +60%
Price
Shares after: 800,000
Date: 08 May 2026
Ownership: See Footnote
Underlying class: Class A Common Stock
Underlying amount: 300,000
Exercise price
Footnotes: F2, F3

WGS transaction Derivative

Cash Settled Swap

Purchase

Transaction value
Shares: +300,000
Change %: +60%
Price
Shares after: 800,000
Date: 08 May 2026
Ownership: See Footnote
Underlying class: Class A Common Stock
Underlying amount: 300,000
Exercise price
Footnotes: F2, F3

WGS transaction Derivative

Cash Settled Swap

Purchase

Transaction value
Shares: +300,000
Change %: +60%
Price
Shares after: 800,000
Date: 08 May 2026
Ownership: See Footnote
Underlying class: Class A Common Stock
Underlying amount: 300,000
Exercise price
Footnotes: F2, F3

WGS transaction Derivative

Cash Settled Swap

Purchase

Transaction value
Shares: +300,000
Change %: +60%
Price
Shares after: 800,000
Date: 08 May 2026
Ownership: See Footnote
Underlying class: Class A Common Stock
Underlying amount: 300,000
Exercise price
Footnotes: F2, F3

WGS transaction Derivative

Cash Settled Swap

Purchase

Transaction value
Shares: +50,000
Change %: +6.2%
Price
Shares after: 850,000
Date: 11 May 2026
Ownership: See Footnote
Underlying class: Class A Common Stock
Underlying amount: 50,000
Exercise price
Footnotes: F2, F4

WGS transaction Derivative

Cash Settled Swap

Purchase

Transaction value
Shares: +50,000
Change %: +6.2%
Price
Shares after: 850,000
Date: 11 May 2026
Ownership: See Footnote
Underlying class: Class A Common Stock
Underlying amount: 50,000
Exercise price
Footnotes: F2, F4

WGS transaction Derivative

Cash Settled Swap

Purchase

Transaction value
Shares: +50,000
Change %: +6.2%
Price
Shares after: 850,000
Date: 11 May 2026
Ownership: See Footnote
Underlying class: Class A Common Stock
Underlying amount: 50,000
Exercise price
Footnotes: F2, F4

WGS transaction Derivative

Cash Settled Swap

Purchase

Transaction value
Shares: +50,000
Change %: +6.2%
Price
Shares after: 850,000
Date: 11 May 2026
Ownership: See Footnote
Underlying class: Class A Common Stock
Underlying amount: 50,000
Exercise price
Footnotes: F2, F4

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 4 footnotes

Footnote F1

Casdin Partners Master Fund, L.P. (the "Master Fund") has entered into certain cash-settled swap agreements (the "Swap Agreements"), which represent economic exposure to an aggregate of 500,000 notional shares of the Issuer's Class A Common Stock, at a price of $38.1543 per share. The Swap Agreements provide the Master Fund with economic results that are comparable to the economic results of ownership but do not provide it with the power to vote or direct the voting or dispose of or direct the disposition of the securities that are referenced by the Swap Agreements.

Footnote F2

The Swap Agreements are owned directly by the Master Fund and may be deemed to be indirectly beneficially owned by (i) Casdin Capital, LLC, the investment adviser to the Master Fund ("Casdin"), (ii) Casdin Partners GP, LLC, the general partner of the Master Fund (the "GP"), and (iii) Eli Casdin, the managing member of Casdin and the GP.

Footnote F3

The Master Fund has entered into certain cash-settled swap agreements (the "Swap Agreements"), which represent economic exposure to an aggregate of 300,000 notional shares of the Issuer's Class A Common Stock, at a price of $41.0261 per share. The Swap Agreements provide the Master Fund with economic results that are comparable to the economic results of ownership but do not provide it with the power to vote or direct the voting or dispose of or direct the disposition of the securities that are referenced by the Swap Agreements.

Footnote F4

The Master Fund has entered into certain cash-settled swap agreements (the "Swap Agreements"), which represent economic exposure to an aggregate of 50,000 notional shares of the Issuer's Class A Common Stock, at a price of $39.6602 per share. The Swap Agreements provide the Master Fund with economic results that are comparable to the economic results of ownership but do not provide it with the power to vote or direct the voting or dispose of or direct the disposition of the securities that are referenced by the Swap Agreements.

SEC remarks

Each Reporting Person disclaims beneficial ownership in the securities reported on this Form 4 except to the extent of its pecuniary interest, if any, therein, and this report shall not be deemed to be an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purpose.