RA CAPITAL MANAGEMENT, L.P. - 04 May 2026 Form 4 Insider Report for Hemab Therapeutics Holdings, Inc. (COAG)

Reporting relationship: Director, 10%+ Owner
Issuer ticker: COAG
Reported as of: 04 May 2026
Net transaction value: $0
SEC form: 4
Accepted by SEC: 06 May 2026, 19:16:36 UTC
Prior SEC filing: 30 Apr 2026
Next SEC filing: 11 May 2026
Source filing: View source filing
Reporting owner signature: /s/ Peter Kolchinsky, Manager of RA Capital Management, L.P.

Filing notes and source

Key filing fact

RA CAPITAL MANAGEMENT, L.P. filed Form 4 for Hemab Therapeutics Holdings, Inc. (COAG) on 06 May 2026.

Key facts

This page summarizes RA CAPITAL MANAGEMENT, L.P.'s Form 4 filing for Hemab Therapeutics Holdings, Inc. (COAG).
15 reported transactions and 36 derivative rows are listed below.
Accepted by SEC: 06 May 2026, 19:16.

Change

Previous filing in this sequence was filed on 30 Apr 2026.
Current net transaction value: $0.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (6)

CIK 0001346824 Primary reporting owner

RA CAPITAL MANAGEMENT, L.P.

Relationship: Director, 10%+ Owner
Address: 200 BERKELEY STREET, 18TH FLOOR, BOSTON
Signature: /s/ Peter Kolchinsky, Manager of RA Capital Management, L.P.
Signature date: 06 May 2026

CIK 0001315082

RA Capital Healthcare Fund LP

Relationship: Director, 10%+ Owner
Address: C/O RA CAPITAL MANAGEMENT, L.P., 200 BERKELEY STREET, 18TH FLOOR, BOSTON
Signature: /s/ Peter Kolchinsky, Manager of RA Capital Healthcare Fund GP, LLC the General Partner of RA Capital Healthcare Fund, L.P.
Signature date: 06 May 2026

CIK 0001825376

RA Capital Nexus Fund II, L.P.

Relationship: Director
Address: C/O RA CAPITAL MANAGEMENT, L.P., 200 BERKELEY STREET, 18TH FLOOR, BOSTON
Signature: /s/ Peter Kolchinsky, Manager of RA Capital Nexus Fund II GP, LLC, the General Partner of RA Capital Nexus Fund II, L.P.
Signature date: 06 May 2026

CIK 0002053586

RA Capital Nexus Fund IV, L.P.

Relationship: Director
Address: C/O RA CAPITAL MANAGEMENT, L.P., 200 BERKELEY STREET, 18TH FLOOR, BOSTON
Signature: /s/ Peter Kolchinsky, Manager of RA Capital Nexus Fund IV GP, LLC, the General Partner of RA Capital Nexus Fund IV, L.P.
Signature date: 06 May 2026

CIK 0001384859

Kolchinsky Peter

Relationship: Director, 10%+ Owner
Address: C/O RA CAPITAL MANAGEMENT, L.P., 200 BERKELEY STREET, 18TH FLOOR, BOSTON
Signature: /s/ Peter Kolchinsky, individually
Signature date: 06 May 2026

CIK 0001619841

Shah Rajeev M.

Relationship: Director, 10%+ Owner
Address: C/O RA CAPITAL MANAGEMENT, L.P., 200 BERKELEY STREET, 18TH FLOOR, BOSTON
Signature: /s/ Rajeev Shah, individually
Signature date: 06 May 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +3,607,846
Change %
Price
Shares after: 3,607,846
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F3

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +3,607,846
Change %
Price
Shares after: 3,607,846
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F3

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +3,607,846
Change %
Price
Shares after: 3,607,846
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F3

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +3,607,846
Change %
Price
Shares after: 3,607,846
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F3

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +3,607,846
Change %
Price
Shares after: 3,607,846
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F3

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +3,607,846
Change %
Price
Shares after: 3,607,846
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F3

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +1,009,052
Change %
Price
Shares after: 1,009,052
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F4

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +1,009,052
Change %
Price
Shares after: 1,009,052
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F4

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +1,009,052
Change %
Price
Shares after: 1,009,052
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F4

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +1,009,052
Change %
Price
Shares after: 1,009,052
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F4

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +1,009,052
Change %
Price
Shares after: 1,009,052
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F4

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +1,009,052
Change %
Price
Shares after: 1,009,052
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F4

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +221,188
Change %
Price
Shares after: 221,188
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F5

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +221,188
Change %
Price
Shares after: 221,188
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F5

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +221,188
Change %
Price
Shares after: 221,188
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F5

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +221,188
Change %
Price
Shares after: 221,188
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F5

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +221,188
Change %
Price
Shares after: 221,188
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F5

COAG transaction

Common Stock

Conversion of derivative security

Transaction value
Shares: +221,188
Change %
Price
Shares after: 221,188
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F1, F2, F5

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +2,541,250
Change %: +70%
Price: $18.00^*
Shares after: 6,149,096
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F2, F3

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +2,541,250
Change %: +70%
Price: $18.00^*
Shares after: 6,149,096
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F2, F3

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +2,541,250
Change %: +70%
Price: $18.00^*
Shares after: 6,149,096
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F2, F3

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +2,541,250
Change %: +70%
Price: $18.00^*
Shares after: 6,149,096
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F2, F3

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +2,541,250
Change %: +70%
Price: $18.00^*
Shares after: 6,149,096
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F2, F3

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +2,541,250
Change %: +70%
Price: $18.00^*
Shares after: 6,149,096
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F2, F3

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +133,750
Change %: +60%
Price: $18.00^*
Shares after: 354,938
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F2, F5

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +133,750
Change %: +60%
Price: $18.00^*
Shares after: 354,938
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F2, F5

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +133,750
Change %: +60%
Price: $18.00^*
Shares after: 354,938
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F2, F5

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +133,750
Change %: +60%
Price: $18.00^*
Shares after: 354,938
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F2, F5

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +133,750
Change %: +60%
Price: $18.00^*
Shares after: 354,938
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F2, F5

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +133,750
Change %: +60%
Price: $18.00^*
Shares after: 354,938
Date: 04 May 2026
Ownership: See footnotes
Footnotes: F2, F5

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +87,143
Change %: +1.4%
Price: $24.59^*
Shares after: 6,236,239
Date: 05 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F6

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +87,143
Change %: +1.4%
Price: $24.59^*
Shares after: 6,236,239
Date: 05 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F6

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +87,143
Change %: +1.4%
Price: $24.59^*
Shares after: 6,236,239
Date: 05 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F6

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +87,143
Change %: +1.4%
Price: $24.59^*
Shares after: 6,236,239
Date: 05 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F6

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +87,143
Change %: +1.4%
Price: $24.59^*
Shares after: 6,236,239
Date: 05 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F6

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +87,143
Change %: +1.4%
Price: $24.59^*
Shares after: 6,236,239
Date: 05 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F6

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +10,268
Change %: +0.16%
Price: $25.00^*
Shares after: 6,246,507
Date: 05 May 2026
Ownership: See footnotes
Footnotes: F2, F3

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +10,268
Change %: +0.16%
Price: $25.00^*
Shares after: 6,246,507
Date: 05 May 2026
Ownership: See footnotes
Footnotes: F2, F3

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +10,268
Change %: +0.16%
Price: $25.00^*
Shares after: 6,246,507
Date: 05 May 2026
Ownership: See footnotes
Footnotes: F2, F3

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +10,268
Change %: +0.16%
Price: $25.00^*
Shares after: 6,246,507
Date: 05 May 2026
Ownership: See footnotes
Footnotes: F2, F3

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +10,268
Change %: +0.16%
Price: $25.00^*
Shares after: 6,246,507
Date: 05 May 2026
Ownership: See footnotes
Footnotes: F2, F3

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +10,268
Change %: +0.16%
Price: $25.00^*
Shares after: 6,246,507
Date: 05 May 2026
Ownership: See footnotes
Footnotes: F2, F3

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +14,611
Change %: +0.23%
Price: $23.77^*
Shares after: 6,261,118
Date: 06 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F7

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +14,611
Change %: +0.23%
Price: $23.77^*
Shares after: 6,261,118
Date: 06 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F7

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +14,611
Change %: +0.23%
Price: $23.77^*
Shares after: 6,261,118
Date: 06 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F7

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +14,611
Change %: +0.23%
Price: $23.77^*
Shares after: 6,261,118
Date: 06 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F7

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +14,611
Change %: +0.23%
Price: $23.77^*
Shares after: 6,261,118
Date: 06 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F7

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +14,611
Change %: +0.23%
Price: $23.77^*
Shares after: 6,261,118
Date: 06 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F7

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +53,407
Change %: +0.85%
Price: $24.83^*
Shares after: 6,314,525
Date: 06 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F8

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +53,407
Change %: +0.85%
Price: $24.83^*
Shares after: 6,314,525
Date: 06 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F8

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +53,407
Change %: +0.85%
Price: $24.83^*
Shares after: 6,314,525
Date: 06 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F8

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +53,407
Change %: +0.85%
Price: $24.83^*
Shares after: 6,314,525
Date: 06 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F8

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +53,407
Change %: +0.85%
Price: $24.83^*
Shares after: 6,314,525
Date: 06 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F8

COAG transaction

Common Stock

Purchase

Transaction value
Shares: +53,407
Change %: +0.85%
Price: $24.83^*
Shares after: 6,314,525
Date: 06 May 2026
Ownership: See footnotes
Footnotes: F2, F3, F8

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

COAG transaction Derivative

Series A Preferred Stock

Conversion of derivative security

Transaction value
Shares: -64,680
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 1,422,960
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series A Preferred Stock

Conversion of derivative security

Transaction value
Shares: -64,680
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 1,422,960
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series A Preferred Stock

Conversion of derivative security

Transaction value
Shares: -64,680
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 1,422,960
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series A Preferred Stock

Conversion of derivative security

Transaction value
Shares: -64,680
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 1,422,960
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series A Preferred Stock

Conversion of derivative security

Transaction value
Shares: -64,680
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 1,422,960
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series A Preferred Stock

Conversion of derivative security

Transaction value
Shares: -64,680
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 1,422,960
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series A Preferred Stock

Conversion of derivative security

Transaction value
Shares: -27,720
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 609,840
Exercise price
Footnotes: F1, F2, F4

COAG transaction Derivative

Series A Preferred Stock

Conversion of derivative security

Transaction value
Shares: -27,720
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 609,840
Exercise price
Footnotes: F1, F2, F4

COAG transaction Derivative

Series A Preferred Stock

Conversion of derivative security

Transaction value
Shares: -27,720
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 609,840
Exercise price
Footnotes: F1, F2, F4

COAG transaction Derivative

Series A Preferred Stock

Conversion of derivative security

Transaction value
Shares: -27,720
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 609,840
Exercise price
Footnotes: F1, F2, F4

COAG transaction Derivative

Series A Preferred Stock

Conversion of derivative security

Transaction value
Shares: -27,720
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 609,840
Exercise price
Footnotes: F1, F2, F4

COAG transaction Derivative

Series A Preferred Stock

Conversion of derivative security

Transaction value
Shares: -27,720
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 609,840
Exercise price
Footnotes: F1, F2, F4

COAG transaction Derivative

Series B Preferred Stock

Conversion of derivative security

Transaction value
Shares: -42,341
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 931,502
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series B Preferred Stock

Conversion of derivative security

Transaction value
Shares: -42,341
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 931,502
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series B Preferred Stock

Conversion of derivative security

Transaction value
Shares: -42,341
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 931,502
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series B Preferred Stock

Conversion of derivative security

Transaction value
Shares: -42,341
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 931,502
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series B Preferred Stock

Conversion of derivative security

Transaction value
Shares: -42,341
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 931,502
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series B Preferred Stock

Conversion of derivative security

Transaction value
Shares: -42,341
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 931,502
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series B Preferred Stock

Conversion of derivative security

Transaction value
Shares: -18,146
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 399,212
Exercise price
Footnotes: F1, F2, F4

COAG transaction Derivative

Series B Preferred Stock

Conversion of derivative security

Transaction value
Shares: -18,146
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 399,212
Exercise price
Footnotes: F1, F2, F4

COAG transaction Derivative

Series B Preferred Stock

Conversion of derivative security

Transaction value
Shares: -18,146
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 399,212
Exercise price
Footnotes: F1, F2, F4

COAG transaction Derivative

Series B Preferred Stock

Conversion of derivative security

Transaction value
Shares: -18,146
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 399,212
Exercise price
Footnotes: F1, F2, F4

COAG transaction Derivative

Series B Preferred Stock

Conversion of derivative security

Transaction value
Shares: -18,146
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 399,212
Exercise price
Footnotes: F1, F2, F4

COAG transaction Derivative

Series B Preferred Stock

Conversion of derivative security

Transaction value
Shares: -18,146
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 399,212
Exercise price
Footnotes: F1, F2, F4

COAG transaction Derivative

Series C Preferred Stock

Conversion of derivative security

Transaction value
Shares: -56,972
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 1,253,384
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series C Preferred Stock

Conversion of derivative security

Transaction value
Shares: -56,972
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 1,253,384
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series C Preferred Stock

Conversion of derivative security

Transaction value
Shares: -56,972
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 1,253,384
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series C Preferred Stock

Conversion of derivative security

Transaction value
Shares: -56,972
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 1,253,384
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series C Preferred Stock

Conversion of derivative security

Transaction value
Shares: -56,972
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 1,253,384
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series C Preferred Stock

Conversion of derivative security

Transaction value
Shares: -56,972
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 1,253,384
Exercise price
Footnotes: F1, F2, F3

COAG transaction Derivative

Series C Preferred Stock

Conversion of derivative security

Transaction value
Shares: -10,054
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 221,188
Exercise price
Footnotes: F1, F2, F5

COAG transaction Derivative

Series C Preferred Stock

Conversion of derivative security

Transaction value
Shares: -10,054
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 221,188
Exercise price
Footnotes: F1, F2, F5

COAG transaction Derivative

Series C Preferred Stock

Conversion of derivative security

Transaction value
Shares: -10,054
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 221,188
Exercise price
Footnotes: F1, F2, F5

COAG transaction Derivative

Series C Preferred Stock

Conversion of derivative security

Transaction value
Shares: -10,054
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 221,188
Exercise price
Footnotes: F1, F2, F5

COAG transaction Derivative

Series C Preferred Stock

Conversion of derivative security

Transaction value
Shares: -10,054
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 221,188
Exercise price
Footnotes: F1, F2, F5

COAG transaction Derivative

Series C Preferred Stock

Conversion of derivative security

Transaction value
Shares: -10,054
Change %: -100%
Price
Shares after: 0
Date: 04 May 2026
Ownership: See footnotes
Underlying class: Common Stock
Underlying amount: 221,188
Exercise price
Footnotes: F1, F2, F5

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 8 footnotes

Footnote F1

Each share of Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into shares of Common Stock immediately prior to the closing of the Issuer's initial public offering for no additional consideration, on a 22-for-1 basis, and had no expiration date.

Footnote F2

RA Capital Management, L.P. (the "Adviser") is the investment manager for RA Capital Healthcare Fund, L.P. (the "Fund"), RA Capital Nexus II Fund, L.P. (the "Nexus Fund II") and RA Capital Nexus IV Fund, L.P. (the "Nexus Fund IV"). The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, the Fund, the Nexus Fund II, the Nexus Fund IV, Dr. Kolchinsky and Mr. Shah disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein.

Footnote F3

Held directly by the Fund.

Footnote F4

Held directly by Nexus Fund II.

Footnote F5

Held directly by Nexus Fund IV.

Footnote F6

The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $24.00 to $24.9994 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

Footnote F7

The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $23.495 to $24.455 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

Footnote F8

The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $24.505 to $25.00 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

SEC remarks

Dr. Laura Tadvalkar, a Managing Director of the Adviser, serves on the Issuer's board of directors.