Crespo Blas Coll - 18 Sep 2025 Form 4 Insider Report for Structure Therapeutics Inc. (GPCR)

Role: CHIEF MEDICAL OFFICER
Signature: /s/ Jun Yoon, Attorney-in-Fact
Issuer symbol: GPCR
Transactions as of: 18 Sep 2025
Net transactions value: -$62,767
Form type: 4
Filing time: 22 Sep 2025, 21:25:04 UTC
Previous filing: 18 Mar 2025
Next filing: 05 Mar 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Coll Crespo Blas	CHIEF MEDICAL OFFICER	C/O STRUCTURE THERAPEUTICS INC., 601 GATEWAY BLVD., SUITE 900, SOUTH SAN FRANCISCO	/s/ Jun Yoon, Attorney-in-Fact	22 Sep 2025	0002037144

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	GPCR	Ordinary Shares	Tax liability	$62,767	-8,106	-3.6%	$7.74	216,807	18 Sep 2025	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.
F2	Represents shares withheld by the Issuer to satisfy income tax obligations associated with the vesting of a restricted share unit award.