| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Manji Husseini | Director | C/O ALTO NEUROSCIENCE, INC., 650 CASTRO STREET, SUITE 450, MOUNTAIN VIEW | /s/ Erin R. McQuade, Attorney-in-Fact | 06 Jan 2026 | 0002009654 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ANRO | Employee Stock Option (right to buy) | Award | $49,975 | +4,228 | $11.82 | 4,228 | 02 Jan 2026 | Common Stock | 4,228 | $16.59 | Direct | F1, F2 |
| Id | Content |
|---|---|
| F1 | 1,057 shares underlying the option shall vest on each of March 31, 2026, June 30, 2026, September 30, 2026 and December 31, 2026, subject to the Reporting Person's continuous service through each such vesting date. |
| F2 | This option was issued to the Reporting Person pursuant to the Issuer's Non-Employee Director Compensation Policy in lieu of retainer fees of $50,000. |