| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Espinoza Octavio | Chief Financial Officer | 555 HERITAGE DRIVE, SUITE 200, JUPITER | By: /s/ Andrew Reardon, Attorney-in-Fact For: Octavio Espinoza | 06 Mar 2026 | 0001905248 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | LGND | Common Stock | Options Exercise | +1,607 | +4.9% | $58.49* | 34,619 | 04 Mar 2026 | Direct | F1 | |
| transaction | LGND | Common Stock | Options Exercise | +466 | +1.3% | $80.72* | 35,085 | 04 Mar 2026 | Direct | F1 | |
| transaction | LGND | Common Stock | Sale | $138,895 | -699 | -2% | $198.71 | 34,386 | 04 Mar 2026 | Direct | F1, F2 |
| transaction | LGND | Common Stock | Sale | $10,604 | -53 | -0.15% | $200.08 | 34,333 | 04 Mar 2026 | Direct | F1, F3 |
| transaction | LGND | Common Stock | Sale | $140,364 | -698 | -2% | $201.09 | 33,635 | 04 Mar 2026 | Direct | F1, F4 |
| transaction | LGND | Common Stock | Sale | $191,640 | -950 | -2.8% | $201.73 | 32,685 | 04 Mar 2026 | Direct | F1, F5 |
| transaction | LGND | Common Stock | Sale | $141,343 | -697 | -2.1% | $202.79 | 31,988 | 04 Mar 2026 | Direct | F1, F6 |
| transaction | LGND | Common Stock | Sale | $136,024 | -668 | -2.1% | $203.63 | 31,320 | 04 Mar 2026 | Direct | F1, F7 |
| transaction | LGND | Common Stock | Sale | $152,125 | -743 | -2.4% | $204.74 | 30,577 | 04 Mar 2026 | Direct | F1, F8 |
| transaction | LGND | Common Stock | Sale | $299,841 | -1,457 | -4.8% | $205.79 | 29,120 | 04 Mar 2026 | Direct | F1, F9 |
| transaction | LGND | Common Stock | Sale | $328,542 | -1,588 | -5.5% | $206.89 | 27,532 | 04 Mar 2026 | Direct | F1, F10 |
| transaction | LGND | Common Stock | Sale | $510,823 | -2,457 | -8.9% | $207.91 | 25,075 | 04 Mar 2026 | Direct | F1, F11 |
| transaction | LGND | Common Stock | Sale | $712,621 | -3,413 | -14% | $208.80 | 21,662 | 04 Mar 2026 | Direct | F1, F12 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | LGND | Employee Stock Option (right to buy) | Options Exercise | -1,607 | -100% | $0.000000* | 0 | 04 Mar 2026 | Common Stock | 1,607 | $58.49 | Direct | F1, F13 | |
| transaction | LGND | Employee Stock Option (right to buy) | Options Exercise | -466 | -100% | $0.000000* | 0 | 04 Mar 2026 | Common Stock | 466 | $80.72 | Direct | F1, F13 |
Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.
Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).
| Id | Content |
|---|---|
| F1 | The transactions reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on November 19, 2025, in accordance with Rule 10b5-1. |
| F2 | The price reported in Column 4 is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $198.3700 to $199.2500. The Reporting Person undertakes to provide the Registrant, any securityholder of the Registrant, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. |
| F3 | The price reported in Column 4 is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $199.4400 to $200.0900. The Reporting Person undertakes to provide the Registrant, any securityholder of the Registrant, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. |
| F4 | The price reported in Column 4 is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $200.5000 to $201.3400. The Reporting Person undertakes to provide the Registrant, any securityholder of the Registrant, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. |
| F5 | The price reported in Column 4 is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $201.4600 to $202.3300. The Reporting Person undertakes to provide the Registrant, any securityholder of the Registrant, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. |
| F6 | The price reported in Column 4 is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $202.4000 to $203.0500. The Reporting Person undertakes to provide the Registrant, any securityholder of the Registrant, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. |
| F7 | The price reported in Column 4 is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $203.4100 to $203.8600. The Reporting Person undertakes to provide the Registrant, any securityholder of the Registrant, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. |
| F8 | The price reported in Column 4 is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $204.4600 to $205.3600. The Reporting Person undertakes to provide the Registrant, any securityholder of the Registrant, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. |
| F9 | The price reported in Column 4 is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $205.3700 to $206.3600. The Reporting Person undertakes to provide the Registrant, any securityholder of the Registrant, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. |
| F10 | The price reported in Column 4 is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $206.4700 to $207.3500. The Reporting Person undertakes to provide the Registrant, any securityholder of the Registrant, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. |
| F11 | The price reported in Column 4 is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $207.4100 to $208.3500. The Reporting Person undertakes to provide the Registrant, any securityholder of the Registrant, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. |
| F12 | The price reported in Column 4 is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $208.3900 to $208.9500. The Reporting Person undertakes to provide the Registrant, any securityholder of the Registrant, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. |
| F13 | The stock option is fully vested and exercisable. |