Jack Higgins - 19 Dec 2025 Form 4 Insider Report for Immunome Inc. (IMNM)

Role: Chief Scientific Officer
Signature: /s/ Sandra Stoneman, Attorney-in-Fact
Issuer symbol: IMNM
Transactions as of: 19 Dec 2025
Net transactions value: $0
Form type: 4
Filing time: 22 Dec 2025, 07:43:46 UTC
Previous filing: 11 Sep 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Higgins Jack	Chief Scientific Officer	C/O IMMUNOME, INC., 18702 N. CREEK PARKWAY, SUITE 100, BOTHELL	/s/ Sandra Stoneman, Attorney-in-Fact	22 Dec 2025	0001993684

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	IMNM	Common Stock	Gift	$0	-1,000	-2.5%	$0.000000	39,729	19 Dec 2025	Direct	F1
transaction	IMNM	Common Stock	Gift	$0	+1,000		$0.000000	1,000	19 Dec 2025	As Custodian for Child 1	F1, F2
transaction	IMNM	Common Stock	Gift	$0	-1,000	-2.5%	$0.000000	38,729	19 Dec 2025	Direct	F1
transaction	IMNM	Common Stock	Gift	$0	+1,000		$0.000000	1,000	19 Dec 2025	As Custodian for Child 2	F1, F2
transaction	IMNM	Common Stock	Gift	$0	-1,000	-2.6%	$0.000000	37,729	19 Dec 2025	Direct	F1
transaction	IMNM	Common Stock	Gift	$0	+1,000		$0.000000	1,000	19 Dec 2025	As Custodian for Child 3	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Reflects the gift of shares by the Reporting Person to a custodial account for the child of the Reporting Person established pursuant to the Uniform Transfer to Minors Act, for which the Reporting Person serves as a custodian. The Reporting Person disclaims beneficial ownership of these shares, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such shares for purposes of Section 16 or for any other purpose.
F2	The shares are subject to a lockup agreement entered into by the Reporting Person on December 15, 2025 (the "Lock-up Agreement"). The transferee has agreed to be bound by the terms of the Lock-up Agreement.

Content

Reflects the gift of shares by the Reporting Person to a custodial account for the child of the Reporting Person established pursuant to the Uniform Transfer to Minors Act, for which the Reporting Person serves as a custodian. The Reporting Person disclaims beneficial ownership of these shares, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such shares for purposes of Section 16 or for any other purpose.

The shares are subject to a lockup agreement entered into by the Reporting Person on December 15, 2025 (the "Lock-up Agreement"). The transferee has agreed to be bound by the terms of the Lock-up Agreement.