Darya Chudova - 01 Sep 2025 Form 4 Insider Report for Guardant Health, Inc. (GH)

Role: Chief Technology Officer
Signature: /s/ John G. Saia, as attorney-in-fact for Darya Chudova
Issuer symbol: GH
Transactions as of: 01 Sep 2025
Net transactions value: -$10,855
Form type: 4
Filing time: 03 Sep 2025, 18:44:54 UTC
Previous filing: 02 Jul 2025
Next filing: 02 Oct 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Chudova Darya	Chief Technology Officer	3100 HANOVER STREET, PALO ALTO	/s/ John G. Saia, as attorney-in-fact for Darya Chudova	03 Sep 2025	0001977179

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	GH	Common Stock	Options Exercise	$0	+316	+0.39%	$0.000000	81,610	01 Sep 2025	Direct
transaction	GH	Common Stock	Tax liability	$10,855	-161	-0.2%	$67.42	81,449	01 Sep 2025	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	GH	Restricted Stock Units	Options Exercise	$0	-316	-100%	$0.000000	0	01 Sep 2025	Common Stock	316	$0.000000	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Not applicable for Restricted Stock Units.
F2	The restricted stock unit award was granted on November 2, 2021, of which 3,157 shares were outstanding on May 3, 2023, when the reporting person was elected as an officer. These shares vest in equal quarterly installments on the anniversary of September 1, 2022 and fully vest on September 1, 2025.