| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Milbury Max A. | Principal Accounting Officer | C/O PROMIS NEUROSCIENCES INC., SUITE 200, 1920 YONGE STREET, TORONTO, ONTARIO, CANADA | /s/ Max A. Milbury | 06 Oct 2025 | 0001927056 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | PMN | Common Shares | Purchase | $14,929 | +30,392 | +203% | $0.4912 | 45,389 | 03 Oct 2025 | Direct |