| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Brudnick Richard | Chief Business Officer | C/O PRIME MEDICINE, INC., 60 FIRST STREET, CAMBRIDGE | /s/ Richard Brudnick | 2025-05-22 | 0001692359 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | PRME | Common Stock | Purchase | $23.8K | +20K | $1.19 | 20K | May 20, 2025 | Direct |