| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Brudnick Richard | Chief Business Officer | C/O PRIME MEDICINE, INC., 60 FIRST STREET, CAMBRIDGE | /s/ Richard Brudnick | 22 May 2025 | 0001692359 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | PRME | Common Stock | Purchase | $23,790 | +20,000 | $1.19 | 20,000 | 20 May 2025 | Direct |