Jonathan Cotliar - Apr 28, 2023 Form 4 Insider Report for Science 37 Holdings, Inc. (SNCE)

Role: Chief Medical Officer
Signature: /s/ Christine Pellizzari, Attorney-in-fact for Jonathan Cotliar
Stock symbol: SNCE
Transactions as of: Apr 28, 2023
Transactions value $: $0
Form type: 4
Date filed: 5/2/2023, 04:24 PM
Previous filing: Aug 16, 2022
Next filing: Aug 15, 2023

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	SNCE	Common Stock	Award		+257K	+37.47%		944K	Apr 28, 2023	Direct	F1, F2, F3

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	SNCE	Stock Option	Disposed to Issuer		-443K	-100%		0	Apr 28, 2023	Common Stock	443K	$10.05	Direct	F1
transaction	SNCE	Stock Option	Disposed to Issuer		-201K	-100%		0	Apr 28, 2023	Common Stock	201K	$11.47	Direct	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	On April 28, 2023, the issuer cancelled, pursuant to the issuer's option exchange program, options to purchase 442,754 shares of common stock of the issuer and in exchange issued to the reporting person 177,101 restricted stock units, each of which represents a contingent right to receive one share of the issuer's common stock.
F2	On April 28, 2023, the issuer cancelled, pursuant to the issuer's option exchange program, options to purchase 200,549 shares of common stock of the issuer and in exchange issued to the reporting person 80,219 restricted stock units, each of which represents a contingent right to receive one share of the issuer's common stock.
F3	Includes 257,320 restricted stock units, which will vest in three equal annual installments beginning on April 28, 2024, subject to continued employment.