Jonathan Cotliar - 20 Apr 2022 Form 4 Insider Report for Science 37 Holdings, Inc.

Role: Chief Medical Officer
Signature: /s/ Christine Pellizzari, Attorney-in-fact for Jonathan Cotliar
Issuer symbol: N/A
Transactions as of: 20 Apr 2022
Net transactions value: +$26,012
Form type: 4
Filing time: 21 Apr 2022, 16:37:14 UTC
Previous filing: 11 Jan 2022
Next filing: 16 Aug 2022
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	SNCE	Common Stock	Options Exercise	$3,319	+3,905	+0.62%	$0.8500	630,037	20 Apr 2022	Direct
transaction	SNCE	Common Stock	Options Exercise	$22,692	+56,731	+9%	$0.4000	686,768	20 Apr 2022	Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	SNCE	Stock Option	Options Exercise	$0	-3,905	-100%	$0.000000^*	0	20 Apr 2022	Common Stock	3,905	$0.8500	Direct	F1
transaction	SNCE	Stock Option	Options Exercise	$0	-56,731	-26%	$0.000000	158,844	20 Apr 2022	Common Stock	56,731	$0.4000	Direct	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Stock Option was fully vested and exercisable as of the date of the transaction.
F2	Stock Option will vest in equal monthly installments until fully vested on June 19, 2023, subject to the executive's continued service through the applicable vesting date.