| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Keswani Sanjay Chandru | Chief Medical Officer | 6027 EDGEWOOD BEND CT., SAN DIEGO | /s/ Darin Lippoldt, Attorney-in-Fact | 17 Feb 2026 | 0001818524 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | NBIX | Stock Option | Award | $0 | +35,827 | $0.000000 | 35,827 | 13 Feb 2026 | Common Stock | 35,827 | $124.12 | Direct | F1 | |
| transaction | NBIX | Restricted Stock Unit | Award | $0 | +6,285 | $0.000000 | 6,285 | 13 Feb 2026 | Common Stock | 6,285 | Direct | F2, F3 |
| Id | Content |
|---|---|
| F1 | Represents option of which 1/48th of the shares underlying the option becomes vested and exercisable on March 13, 2026 and an additional 1/48th of the shares underlying the option becomes vested and exercisable each month thereafter. |
| F2 | Each RSU represents a contingent right to receive one share of the Issuer's common stock. |
| F3 | The Restricted Stock Units will vest annually at 1/4 of the units vesting on each of February 13, 2027, February 13, 2028, February 13, 2029, and February 13, 2030. |