Michael Overdorf - 18 Feb 2026 Form 4 Insider Report for Annexon, Inc. (ANNX)

Role: EVP & CHIEF BUSINESS OFFICER
Signature: /s/ Jennifer Lew, Attorney-in-Fact
Issuer symbol: ANNX
Transactions as of: 18 Feb 2026
Net transactions value: -$31,748
Form type: 4
Filing time: 20 Feb 2026, 16:30:09 UTC
Previous filing: 16 Jul 2025
Next filing: 23 Feb 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Overdorf Michael	EVP & CHIEF BUSINESS OFFICER	C/O ANNEXON, INC, 1400 SIERRA POINT PKWY, BLDG C, STE 200, BRISBANE	/s/ Jennifer Lew, Attorney-in-Fact	20 Feb 2026	0001818522

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	ANNX	Common Stock	Sale	$31,748	-6,225	-4.8%	$5.10	124,464	18 Feb 2026	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The shares were sold to cover tax withholding obligations in connection with the vesting of restricted stock units ("RSUs").
F2	This transaction was executed in multiple trades in prices ranging from $4.93 to $5.16, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

Content

The shares were sold to cover tax withholding obligations in connection with the vesting of restricted stock units ("RSUs").

This transaction was executed in multiple trades in prices ranging from $4.93 to $5.16, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.