| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Alam Kamran | CHIEF FINANCIAL OFFICER | C/O TAYSHA GENE THERAPIES, INC., 3000 PEGASUS PARK DRIVE, STE 1430, DALLAS | /s/ Kamran Alam, Attorney-in-Fact | 14 Jan 2026 | 0001793412 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | TSHA | Common Stock | Award | $0 | +359,000 | +30% | $0.000000 | 1,546,603 | 12 Jan 2026 | Direct | F1 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | TSHA | Employee Stock Option (right to buy) | Award | $0 | +231,000 | $0.000000 | 231,000 | 12 Jan 2026 | Common Stock | 231,000 | $4.86 | Direct | F2 |
| Id | Content |
|---|---|
| F1 | Represents a restricted stock unit ("RSU") award. The RSUs will vest in four equal annual installments beginning on January 12, 2027, subject to the Reporting Person's continuous service through each applicable vesting date. |
| F2 | 25% of the total number of shares underlying the option shall vest and become exercisable on January 12, 2027 and the remainder shall vest and become exercisable in 36 equal monthly installments thereafter, subject to the Reporting Person's continuous service through each applicable vesting date. |