| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Patil Neena M | EVP & Chief Legal Officer | 5TH FL, WATERLOO EXCHANGE, WATERLOO RD, DUBLIN 4, IRELAND | By: /s/Paz Dizon, as attorney in fact For: Neena Patil | 02 Mar 2026 | 0001783908 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | JAZZ | Ordinary Shares | Options Exercise | $2,276,138 | +20,125 | +38% | $113.10 | 73,464 | 26 Feb 2026 | Direct | |
| transaction | JAZZ | Ordinary Shares | Sale | $3,196,335 | -16,602 | -23% | $192.53 | 56,862 | 26 Feb 2026 | Direct | F1 |
| transaction | JAZZ | Ordinary Shares | Options Exercise | $98,962 | +875 | +1.5% | $113.10 | 57,737 | 26 Feb 2026 | Direct | |
| transaction | JAZZ | Ordinary Shares | Sale | $168,057 | -875 | -1.5% | $192.07 | 56,862 | 26 Feb 2026 | Direct | F2 |
| transaction | JAZZ | Ordinary Shares | Options Exercise | $3,713,758 | +27,084 | +48% | $137.12 | 83,946 | 26 Feb 2026 | Direct | |
| transaction | JAZZ | Ordinary Shares | Sale | $2,959,807 | -15,555 | -19% | $190.28 | 68,391 | 26 Feb 2026 | Direct | F3 |
| transaction | JAZZ | Ordinary Shares | Options Exercise | $399,842 | +2,916 | +4.3% | $137.12 | 71,307 | 26 Feb 2026 | Direct | |
| transaction | JAZZ | Ordinary Shares | Sale | $553,491 | -2,916 | -4.1% | $189.81 | 68,391 | 26 Feb 2026 | Direct | F4 |
| transaction | JAZZ | Ordinary Shares | Award | $0 | +10,079 | +15% | $0.000000 | 78,470 | 26 Feb 2026 | Direct | F5 |
| transaction | JAZZ | Ordinary Shares | Sale | $2,209,481 | -11,529 | -15% | $191.65 | 66,941 | 26 Feb 2026 | Direct | F6 |
| transaction | JAZZ | Ordinary Shares | Sale | $681,993 | -3,523 | -5.3% | $193.58 | 63,418 | 26 Feb 2026 | Direct | F7 |
| transaction | JAZZ | Ordinary Shares | Sale | $201,594 | -1,061 | -1.7% | $190.00 | 62,357 | 26 Feb 2026 | Direct | F8 |
| transaction | JAZZ | Ordinary Shares | Sale | $104,747 | -549 | -0.88% | $190.80 | 61,808 | 26 Feb 2026 | Direct | F9 |
| transaction | JAZZ | Ordinary Shares | Sale | $342,312 | -1,784 | -2.9% | $191.88 | 60,024 | 26 Feb 2026 | Direct | F10 |
| transaction | JAZZ | Ordinary Shares | Sale | $194,527 | -1,009 | -1.7% | $192.79 | 59,015 | 26 Feb 2026 | Direct | F11 |
| transaction | JAZZ | Ordinary Shares | Sale | $38,139 | -197 | -0.33% | $193.60 | 58,818 | 26 Feb 2026 | Direct | F12 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | JAZZ | Incentive Stock Option (right to buy) | Options Exercise | $0 | -875 | -100% | $0.000000 | 0 | 26 Feb 2026 | Ordinary Shares | 875 | $113.10 | Direct | F13 |
| transaction | JAZZ | Incentive Stock Option (right to buy) | Options Exercise | $0 | -2,916 | -100% | $0.000000 | 0 | 26 Feb 2026 | Ordinary Shares | 2,916 | $137.12 | Direct | F14 |
| transaction | JAZZ | Non-Qualified Stock Option (right to buy) | Options Exercise | $0 | -20,125 | -100% | $0.000000 | 0 | 26 Feb 2026 | Ordinary Shares | 20,125 | $113.10 | Direct | F13 |
| transaction | JAZZ | Non-Qualified Stock Option (right to buy) | Options Exercise | $0 | -27,084 | -100% | $0.000000 | 0 | 26 Feb 2026 | Ordinary Shares | 27,084 | $137.12 | Direct | F14 |
| Id | Content |
|---|---|
| F1 | Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $192.1100 to $193.0100. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected. |
| F2 | Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $192.0600 to $192.1100. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected. |
| F3 | Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $189.9150 to $190.9000. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected. |
| F4 | Reflects the sale of ordinary shares executed in multiple transactions at prices ranging from $189.7300 to $189.9150. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected. |
| F5 | These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of March 5, 2026, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years. |
| F6 | Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $191.3200 to $192.0600. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected. |
| F7 | Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $193.2900 to $193.8400. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected. |
| F8 | Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $189.395 to $190.3700. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected. |
| F9 | Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $190.4100 to $191.2150. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected. |
| F10 | Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $191.4750 to $192.4300. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected. |
| F11 | Reflects the sale of ordinary shares executed in multiple transactions at prices ranging from $192.4600 to $193.4500. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected. |
| F12 | Reflects the sale of ordinary shares executed in multiple transactions at prices ranging from $193.5300 to $193.6700. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected. |
| F13 | These options are granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the grant date, February 27, 2020, with 1/4th vesting on the first anniversary of the grant date and the remainder vesting in 36 equal monthly installments thereafter. |
| F14 | These options are granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the vesting commencement date of July 29, 2019, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in 36 equal monthly installments thereafter. |