Jacqueline E. Shea - 26 Feb 2026 Form 4 Insider Report for INOVIO PHARMACEUTICALS, INC. (INO)

Role: Chief Executive Officer, Director
Signature: /s/ Jacqueline E. Shea
Issuer symbol: INO
Transactions as of: 26 Feb 2026
Net transactions value: -$38,868
Form type: 4
Filing time: 27 Feb 2026, 16:47:50 UTC
Previous filing: 21 May 2025
Next filing: 05 Mar 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Shea Jacqueline Elizabeth	Chief Executive Officer, Director	660 W. GERMANTOWN PIKE, PLYMOUTH MEETING	/s/ Jacqueline E. Shea	27 Feb 2026	0001771498

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	INO	Common Stock	Options Exercise		+18,632	+31%		78,317	26 Feb 2026	Direct	F1
transaction	INO	Common Stock	Tax liability	$14,422	-8,057	-10%	$1.79	70,260	26 Feb 2026	Direct	F2
transaction	INO	Common Stock	Options Exercise		+28,401	+40%		98,661	26 Feb 2026	Direct	F3
transaction	INO	Common Stock	Tax liability	$24,446	-13,657	-14%	$1.79	85,004	26 Feb 2026	Direct	F4

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	INO	Restricted Stock Unit	Options Exercise	$0	-18,632	-50%	$0.000000	18,631	26 Feb 2026	Common Stock	18,632		Direct	F1
transaction	INO	Restricted Stock Unit	Options Exercise	$0	-28,401	-33%	$0.000000	56,800	26 Feb 2026	Common Stock	28,401		Direct	F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 55,895 restricted stock units granted on February 28, 2024 was as follows: 18,632 shares vested on February 26, 2025; 18,632 shares vested on February 26, 2026; and 18,631 shares will vest on February 26, 2027. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.
F2	The transaction reported represents the withholding of shares by the issuer to satisfy the reporting person's tax withholding obligations in connection with the vesting and settlement of the restricted stock unit award reported in the immediately preceding row and described in footnote (1) herein.
F3	Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 85,201 restricted stock units granted on February 27, 2025 was as follows: 28,401 shares vested on February 26, 2026; 28,400 shares will vest on February 26, 2027; 28,400 shares will vest on February 26, 2028. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.
F4	The transaction reported represents the withholding of shares by the issuer to satisfy the reporting person's tax withholding obligations in connection with the vesting and settlement of the restricted stock unit award reported in the immediately preceding row and described in footnote (3) herein.