Alise Reicin - 25 Sep 2025 Form 4 Insider Report for Tectonic Therapeutic, Inc. (TECX)

Role: Chief Executive Officer, Director
Signature: /s/ Daniel Lochner, Attorney-in-Fact
Issuer symbol: TECX
Transactions as of: 25 Sep 2025
Net transactions value: $0
Form type: 4
Filing time: 29 Sep 2025, 17:00:05 UTC
Previous filing: 24 Jun 2025
Next filing: 05 Jan 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
REICIN ALISE	Chief Executive Officer, Director	C/O TECTONIC THERAPEUTIC, INC., 490 ARSENAL WAY, SUITE 210, WATERTOWN	/s/ Daniel Lochner, Attorney-in-Fact	29 Sep 2025	0001757533

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	TECX	Common Stock	Award	$0	+14,700	+6.9%	$0.000000	228,185	25 Sep 2025	Direct	F1
holding	TECX	Common Stock						124,530	25 Sep 2025	By Trust	F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	TECX	Employee Stock Option (Right to Buy)	Award	$0	+26,710		$0.000000	26,710	25 Sep 2025	Common Stock	26,710	$14.71	Direct	F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	These shares are represented by restricted stock units. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. The shares shall vest in 3 equal annual installments on each of September 25, 2026, September 25, 2027 and September 25, 2028, subject to the Reporting Person's continued service to the Issuer on each such vesting date.
F2	These shares are held by the Reicin-Boiarsky Family Trust (the "Trust"). The Reporting Person's spouse is a co-trustee of the Trust. Accordingly, the Reporting Person may be deemed to have shared voting and dispositive power over the securities held by the Trust. The Reporting Person disclaims beneficial ownership of the shares held by the Trust except to the extent of her pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose.
F3	The shares subject to the option vest in 48 equal monthly installments beginning on October 25, 2025, subject to the Reporting Person's continued service to the Issuer on each such vesting date.