Meredith Manning - 15 Dec 2025 Form 4 Insider Report for SOLENO THERAPEUTICS INC (SLNO)

Role: Chief Commercial Officer
Signature: /s/ Anish Bhatnagar, Attorney-in-Fact
Issuer symbol: SLNO
Transactions as of: 15 Dec 2025
Net transactions value: -$96,004
Form type: 4
Filing time: 17 Dec 2025, 16:38:30 UTC
Previous filing: 31 Mar 2025
Next filing: 23 Jan 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Manning Meredith	Chief Commercial Officer	100 MARINE PARKWAY, SUITE 400, REDWOOD CITY	/s/ Anish Bhatnagar, Attorney-in-Fact	17 Dec 2025	0001752631

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	SLNO	Common Stock	Tax liability	$96,004	-1,922	-4.2%	$49.95	43,429	15 Dec 2025	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents shares that have been withheld by the Issuer to satisfy the Reporting Person's tax withholding obligations in connection with the settlement of restricted stock units ("RSUs") which vested on December 15, 2025.
F2	Certain of these securities are RSUs. Each RSU represents a contingent right to receive one share of Common Stock, subject to the applicable vesting schedule and conditions of each RSU.