Yvonne Greenstreet - 27 Feb 2026 Form 4 Insider Report for ALNYLAM PHARMACEUTICALS, INC. (ALNY)

Role
Chief Executive Officer, Director
Signature
By: Brett Budzinski, Attorney-in-Fact For: Yvonne Greenstreet
Issuer symbol
ALNY
Transactions as of
27 Feb 2026
Net transactions value
$0
Form type
4
Filing time
02 Mar 2026, 16:10:11 UTC
Previous filing
17 Feb 2026
Next filing
04 Mar 2026
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Greenstreet Yvonne Chief Executive Officer, Director 675 WEST KENDALL STREET, HENRI A. TERMEER SQUARE, CAMBRIDGE By: Brett Budzinski, Attorney-in-Fact For: Yvonne Greenstreet 02 Mar 2026 0001446125

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction ALNY Common Stock Options Exercise $0 +5,921 +6.9% $0.000000 91,583 27 Feb 2026 Direct
holding ALNY Common Stock 407 27 Feb 2026 by Managed Account F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction ALNY Restricted Stock Units Options Exercise $0 -5,921 -100% $0.000000 0 27 Feb 2026 Common Stock 5,921 Direct F2, F3, F4
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 Reflects shares of ALNY common stock acquired by the Reporting Person under the issuer 401(k) plan as a result of the issuer 401(k) matching contribution program.
F2 These shares are represented by restricted stock units (RSUs) granted under the Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock.
F3 On February 27, 2023, the reporting person was granted 17,763 restricted stock units that vest ratably on each of the first, second and third anniversaries of the Grant Date. On February 27, 2026, the third and final tranche of restricted stock units from the February 27, 2023 grant vested and was released, as reported on this Form 4.
F4 The restricted stock units vest ratably in three installments, with one third vesting on each of the first, second and third anniversaries of the grant date.