Yvonne Greenstreet - 02 May 2025 Form 4 Insider Report for ALNYLAM PHARMACEUTICALS, INC. (ALNY)

Role: Chief Executive Officer, Director
Signature: By: Brett Budzinski, Attorney-in-Fact For: Yvonne Greenstreet
Issuer symbol: ALNY
Transactions as of: 02 May 2025
Net transactions value: $0
Form type: 4
Filing time: 06 May 2025, 17:05:38 UTC
Previous filing: 05 Mar 2025
Next filing: 19 May 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Greenstreet Yvonne	Chief Executive Officer, Director	675 WEST KENDALL STREET, HENRI A. TERMEER SQUARE, CAMBRIDGE	By: Brett Budzinski, Attorney-in-Fact For: Yvonne Greenstreet	06 May 2025	0001446125

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	ALNY	Common Stock	Gift	$0	-41,311	-42%	$0.000000	57,324	02 May 2025	Direct	F1
holding	ALNY	Common Stock						407	02 May 2025	by Managed Account	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The reported transaction involves a transfer of securities by bona fide gift for estate planning purposes to the Yvonne Greenstreet 2024 Irrevocable Trust Dtd 10/29/2024, of which the reporting person is neither the trustee nor a beneficiary.
F2	Reflects shares of ALNY common stock acquired by the Reporting Person under the issuer 401(k) plan as a result of the issuer 401(k) matching contribution program.