| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ALNY | Common Stock | Options Exercise | $0 | +1,908 | +16% | $0.000000 | 13,897 | 27 Feb 2025 | Direct | |
| transaction | ALNY | Common Stock | Sale | $12,062 | -51 | -0.37% | $236.51 | 13,846 | 28 Feb 2025 | Direct | F1, F2 |
| transaction | ALNY | Common Stock | Sale | $9,533 | -40 | -0.29% | $238.33 | 13,806 | 28 Feb 2025 | Direct | F1, F3 |
| transaction | ALNY | Common Stock | Sale | $9,806 | -41 | -0.3% | $239.18 | 13,765 | 28 Feb 2025 | Direct | F1, F4 |
| transaction | ALNY | Common Stock | Sale | $21,869 | -91 | -0.66% | $240.32 | 13,674 | 28 Feb 2025 | Direct | F1, F5 |
| transaction | ALNY | Common Stock | Sale | $35,985 | -149 | -1.1% | $241.51 | 13,525 | 28 Feb 2025 | Direct | F1, F6 |
| transaction | ALNY | Common Stock | Sale | $85,339 | -352 | -2.6% | $242.44 | 13,173 | 28 Feb 2025 | Direct | F1, F7 |
| transaction | ALNY | Common Stock | Sale | $34,539 | -142 | -1.1% | $243.23 | 13,031 | 28 Feb 2025 | Direct | F1, F8 |
| transaction | ALNY | Common Stock | Sale | $16,844 | -69 | -0.53% | $244.11 | 12,962 | 28 Feb 2025 | Direct | F1, F9 |
| holding | ALNY | Common Stock | 431 | 27 Feb 2025 | by Managed Account | F10 | |||||
| holding | ALNY | Common Stock | 250 | 27 Feb 2025 | by Trust | F11 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ALNY | Restricted Stock Units | Options Exercise | $0 | -1,908 | -50% | $0.000000 | 1,908 | 27 Feb 2025 | Common Stock | 1,908 | Direct | F12, F13 |
| Id | Content |
|---|---|
| F1 | Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the award agreement required to cover minimum statutory tax withholding obligations that became due upon the vesting and settlement of restricted stock units reported in this form. |
| F2 | The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $236.50 to $237.00. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. |
| F3 | The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $237.72 to $238.72. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. |
| F4 | The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $238.73 to $239.69. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. |
| F5 | The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $239.82 to $240.79. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. |
| F6 | The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $240.85 to $241.85. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. |
| F7 | The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $241.86 to $242.86. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. |
| F8 | The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $242.87 to $243.84. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. |
| F9 | The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $243.90 to $244.32. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. |
| F10 | Reflects shares of ALNY common stock acquired by the Reporting Person under the issuer 401(k) plan as a result of the issuer 401(k) matching contribution program. |
| F11 | Represents shares held in trust, of which the Reporting Persons spouse is co-trustee. The Reporting Person disclaims beneficial ownership of these shares, and the filing of this report is not an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose. |
| F12 | These shares are represented by restricted stock units (RSUs) granted under the Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. |
| F13 | On February 27, 2023, the reporting person was granted 5,724 restricted stock units that vest ratably on each of the first, second and third anniversaries of the Grant Date. On February 27, 2025, the second tranche of restricted stock units from the February 27, 2023 grant vested and was released, as reported on this Form 4. |