| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ALNY | Common Stock | Options Exercise | $241,251 | +33,979 | +16% | $7.10* | 248,744 | 13 Aug 2021 | Direct | F1 |
| transaction | ALNY | Common Stock | Sale | $483,367 | -2,441 | -0.98% | $198.02 | 246,303 | 13 Aug 2021 | Direct | F1, F2 |
| transaction | ALNY | Common Stock | Sale | $827,549 | -4,160 | -1.7% | $198.93 | 242,143 | 13 Aug 2021 | Direct | F1, F3 |
| transaction | ALNY | Common Stock | Sale | $4,665,333 | -23,336 | -9.6% | $199.92 | 218,807 | 13 Aug 2021 | Direct | F1, F4 |
| transaction | ALNY | Common Stock | Sale | $768,816 | -3,828 | -1.7% | $200.84 | 214,979 | 13 Aug 2021 | Direct | F1, F5 |
| transaction | ALNY | Common Stock | Sale | $43,132 | -214 | -0.1% | $201.55 | 214,765 | 13 Aug 2021 | Direct | F1 |
| holding | ALNY | Common Stock | 3,133 | 13 Aug 2021 | by Managed Account | F6 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ALNY | Stock Option (right to buy) | Options Exercise | $0 | -33,979 | -50% | $0.000000 | 33,978 | 13 Aug 2021 | Common Stock | 33,979 | $7.10 | Direct | F1, F7 |
| Id | Content |
|---|---|
| F1 | All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 9, 2020. The 33,979 options exercised and sold by the reporting person were due to expire on November 30, 2021. |
| F2 | Sale prices ranged from $197.44 to $198.44. |
| F3 | Sale prices ranged from $198.45 to $199.44. |
| F4 | Sale prices ranged from $199.46 to $200.45. |
| F5 | Sale prices ranged from $200.48 to $201.43. |
| F6 | Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program. |
| F7 | The stock option vested as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter. |