| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Harsch Mutya | CHIEF LEGAL OFFICER AND GC | C/O VYNE THERAPEUTICS INC., 685 ROUTE 202/206 N, SUITE 301, BRIDGEWATER | /s/ Mutya Harsch, Attorney-in-Fact | 02 Oct 2025 | 0001727809 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | VYNE | Common Stock | Tax liability | $1,200 | -3,581 | -2.7% | $0.3350 | 129,484 | 30 Sep 2025 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | Represents shares that have been withheld by the Issuer to satisfy tax withholding requirements in connection with the vesting of restricted stock units. |