| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Domzalski David | PRESIDENT AND CEO, Director | C/O VYNE THERAPEUTICS INC., P.O. BOX 125, STEWARTSVILLE | /s/ Mutya Harsch, Attorney-in-Fact | 05 Jan 2026 | 0001727794 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | VYNE | Common Stock | Tax liability | $7,358 | -12,684 | -3% | $0.5801 | 416,208 | 31 Dec 2025 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | Represents shares that have been withheld by the Issuer to satisfy tax withholding requirements in connection with the vesting of restricted stock units. |