| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Stuart Iain | CHIEF SCIENTIFIC OFFICER | C/O VYNE THERAPEUTICS INC., P.O. BOX 125, STEWARTSVILLE | /s/ Mutya Harsch, Attorney-in-Fact | 05 Jan 2026 | 0001727756 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | VYNE | Common Stock | Tax liability | $1,420 | -2,448 | -2.1% | $0.5801 | 115,239 | 31 Dec 2025 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | Represents shares that have been withheld by the Issuer to satisfy tax withholding requirements in connection with the vesting of restricted stock units. |