Michael Brian Bell - 15 Mar 2026 Form 4 Insider Report for Guardant Health, Inc. (GH)

Role: Chief Financial Officer
Signature: /s/ John G. Saia, as attorney-in-fact for Michael Brian Bell
Issuer symbol: GH
Transactions as of: 15 Mar 2026
Net transactions value: -$261,111
Form type: 4
Filing time: 17 Mar 2026, 18:46:18 UTC
Previous filing: 13 Mar 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Bell Michael Brian	Chief Financial Officer	3100 HANOVER STREET, PALO ALTO	/s/ John G. Saia, as attorney-in-fact for Michael Brian Bell	17 Mar 2026	0001702824

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	GH	Common Stock	Options Exercise		+1,233	+3.1%	$0.000000^*	41,457	15 Mar 2026	Direct
transaction	GH	Common Stock	Options Exercise		+10,518	+25%	$0.000000^*	51,975	15 Mar 2026	Direct
transaction	GH	Common Stock	Options Exercise		+2,039	+3.9%	$0.000000^*	54,014	15 Mar 2026	Direct
transaction	GH	Common Stock	Tax liability		-7,413	-14%	$85.49^*	46,601	15 Mar 2026	Direct	F1
transaction	GH	Common Stock	Sale	$261,111	-3,000	-6.4%	$87.04	43,601	16 Mar 2026	Direct	F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	GH	Restricted Stock Units	Options Exercise		-1,233	-100%	$0.000000^*	0	15 Mar 2026	Common Stock	1,233	$0.000000	Direct	F3, F4
transaction	GH	Performance-Based Restricted Stock Units	Options Exercise		-10,518	-100%	$0.000000^*	0	15 Mar 2026	Common Stock	10,518	$0.000000	Direct	F4, F5
transaction	GH	Restricted Stock Units	Options Exercise		-2,039	-50%	$0.000000^*	2,039	15 Mar 2026	Common Stock	2,039	$0.000000	Direct	F4, F6

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.
F2	Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $87.0001 to $87.1500. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.
F3	This represents a restricted stock unit award granted on May 9, 2022 that vested over a four-year period. 25% of the shares subject to such award vested on March 15, 2023 and the remaining 75% of the shares vested in equal quarterly installments over the remaining three-year period thereafter.
F4	Not applicable for Restricted Stock Units.
F5	This represents a performance-based restricted stock unit award granted on June 7, 2023 with a 3-year performance metric. The second tranche metric was achieved and the shares vested on March 15, 2026.
F6	This represents a restricted stock unit award granted on June 9, 2023 that vests over a three-year period. 33% of the shares subject to such award vested on June 15, 2024 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.