| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Shah Nimish P | Director | C/O VENROCK, 7 BRYANT PARK, 23RD FLOOR, NEW YORK | Nimish Shah, By: /s/ Sherman G. Souther, Attorney-infact | 15 Oct 2025 | 0001698082 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | APGE | Pre-Funded Warrants (Right to Buy) | Purchase | $14,999,936 | +365,853 | $41.00 | 365,853 | 10 Oct 2025 | Common Stock | 365,853 | See footnotes | F1, F2, F3 |
| Id | Content |
|---|---|
| F1 | The exercise price is $0.00001 per share. |
| F2 | The Pre-Funded Warrants have no expiration date and are exercisable immediately. Notwithstanding the foregoing, Venrock Opportunities Fund, L.P. ("VOF") shall not be entitled to exercise the Pre-Funded Warrants to the extent that such exercise would cause the aggregate number of shares of Common Stock beneficially owned by VOF, its affiliates and any persons whose ownership would be aggregated with VOF's for purposes of Section 13(d) of the Securities Exchange Act to exceed 4.99% of the total number of issued and outstanding shares of Common Stock of the Issuer following such exercise. |
| F3 | Securities are held directly by VOF. Venrock Opportunities Management, LLC ("VO Management") is the general partner of VOF. The Reporting Person is a voting member of VO Management and expressly disclaims beneficial ownership over all shares held by VOF except to the extent of his indirect pecuniary interests therein. |