Jeffrey B. Kindler - 06 Feb 2026 Form 4 Insider Report for Praxis Precision Medicines, Inc. (PRAX)

Role: Director
Signature: /s/ Alex Nemiroff, as Attorney-in-Fact
Issuer symbol: PRAX
Transactions as of: 06 Feb 2026
Net transactions value: $0
Form type: 4
Filing time: 10 Feb 2026, 16:57:40 UTC
Previous filing: 02 Feb 2026
Next filing: 12 Mar 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
KINDLER JEFFREY B	Director	C/O PRAXIS PRECISION MEDICINES, INC., 99 HIGH STREET, 30TH FLOOR, BOSTON	/s/ Alex Nemiroff, as Attorney-in-Fact	10 Feb 2026	0001174454

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	PRAX	Common Stock	Award	$0	+688		$0.000000	688	06 Feb 2026	Direct	F1
transaction	PRAX	Common Stock	Award	$0	+478	+69%	$0.000000	1,166	06 Feb 2026	Direct	F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	PRAX	Stock Option (Right to Buy)	Award	$0	+224		$0.000000	224	06 Feb 2026	Common Stock	224	$319.57	Direct	F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Mr. Kindler was awarded 688 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The restricted stock units vest in two equal annual installments occurring on the first two anniversaries of January 8, 2026. The restricted stock units may be settled only by delivering shares of the Issuer's common stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.
F2	Mr. Kindler was awarded 478 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The restricted stock units vest in a single annual installment on the earlier of (i) June 26, 2026 or (ii) the date of the Issuer's 2026 annual meeting of stockholders. The restricted stock units may be settled only by delivering shares of the Issuer's common stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.
F3	The shares subject to this option shall vest in equal monthly installments occurring on the 26th day of each month, with the first such installment occurring on February 26, 2026 and the final such installment occurring on the earlier of (i) June 26, 2026 or (ii) the date of the Issuer's 2026 annual meeting of stockholders.