| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Reeve Emma | Director | C/O PTC THERAPEUTICS, INC., 500 WARREN CORPORATE CENTER DRIVE, WARREN | /s/ Avraham S. Adler, Attorney-in-Fact | 07 Oct 2025 | 0001680329 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | PTCT | Common Stock | Options Exercise | $394,200 | +10,000 | +97% | $39.42 | 20,332 | 03 Oct 2025 | Direct | F1 |
| transaction | PTCT | Common Stock | Sale | $197,093 | -3,028 | -15% | $65.09 | 17,304 | 03 Oct 2025 | Direct | F1, F2 |
| transaction | PTCT | Common Stock | Sale | $303,419 | -4,591 | -27% | $66.09 | 12,713 | 03 Oct 2025 | Direct | F1, F3 |
| transaction | PTCT | Common Stock | Sale | $159,217 | -2,381 | -19% | $66.87 | 10,332 | 03 Oct 2025 | Direct | F1, F4 |
| transaction | PTCT | Common Stock | Options Exercise | $228,234 | +6,912 | +67% | $33.02 | 17,244 | 03 Oct 2025 | Direct | F1 |
| transaction | PTCT | Common Stock | Sale | $140,638 | -2,163 | -13% | $65.02 | 15,081 | 03 Oct 2025 | Direct | F1, F5 |
| transaction | PTCT | Common Stock | Sale | $208,180 | -3,149 | -21% | $66.11 | 11,932 | 03 Oct 2025 | Direct | F1, F6 |
| transaction | PTCT | Common Stock | Sale | $107,088 | -1,600 | -13% | $66.93 | 10,332 | 03 Oct 2025 | Direct | F1, F7 |
| transaction | PTCT | Common Stock | Options Exercise | $290,900 | +8,650 | +84% | $33.63 | 18,982 | 03 Oct 2025 | Direct | F1 |
| transaction | PTCT | Common Stock | Sale | $177,521 | -2,729 | -14% | $65.05 | 16,253 | 03 Oct 2025 | Direct | F1, F8 |
| transaction | PTCT | Common Stock | Sale | $266,846 | -4,037 | -25% | $66.10 | 12,216 | 03 Oct 2025 | Direct | F1, F9 |
| transaction | PTCT | Common Stock | Sale | $126,021 | -1,884 | -15% | $66.89 | 10,332 | 03 Oct 2025 | Direct | F1, F10 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | PTCT | Stock Option (Right to Buy) | Options Exercise | $0 | -10,000 | -100% | $0.000000 | 0 | 03 Oct 2025 | Common Stock | 10,000 | $33.63 | Direct | F1, F11 |
| transaction | PTCT | Stock Option (Right to Buy) | Options Exercise | $0 | -6,912 | -100% | $0.000000 | 0 | 03 Oct 2025 | Common Stock | 6,912 | $33.02 | Direct | F1, F11 |
| transaction | PTCT | Stock Option (Right to Buy) | Options Exercise | $0 | -8,650 | -100% | $0.000000 | 0 | 03 Oct 2025 | Common Stock | 8,650 | $33.63 | Direct | F1, F11 |
Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.
Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).
| Id | Content |
|---|---|
| F1 | This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on March 4, 2025. |
| F2 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $64.50 to $65.49 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F3 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $65.50 to $66.49 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F4 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $66.50 to $67.29 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F5 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $64.50 to $65.49 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F6 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $65.50 to $66.48 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F7 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $66.61 to $67.33 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F8 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $64.50 to $65.49 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F9 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $65.50 to $66.46 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F10 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $66.61 to $67.28 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F11 | Currently exercisable. |