| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Fairmount Funds Management LLC | Director | 200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN | /s/ Tomas Kiselak, Managing Member of Fairmount Funds Management LLC | 02 Jun 2025 | 0001802528 |
| Harwin Peter Evan | Director | 200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN | /s/ Tomas Kiselak | 02 Jun 2025 | 0001663607 |
| Kiselak Tomas | Director | 200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN | /s/ Peter Harwin | 02 Jun 2025 | 0001830177 |
| Fairmount Healthcare Fund II L.P. | Director | 200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN | /s/ Tomas Kiselak, Managing Member of Fairmount Healthcare Fund II L.P. | 02 Jun 2025 | 0001769651 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | SYRE | Stock Option (Right to Buy) | Award | $0 | +25,000 | $0.000000 | 25,000 | 29 May 2025 | Common Stock | 25,000 | $15.55 | By Peter Harwin | F1, F2 | |
| transaction | SYRE | Stock Option (Right to Buy) | Award | $0 | +25,000 | $0.000000 | 25,000 | 29 May 2025 | Common Stock | 25,000 | $15.55 | By Tomas Kiselak | F3, F4 |
| Id | Content |
|---|---|
| F1 | This option represents a right to purchase 25,000 shares of the Issuer's common stock, which will vest and become exercisable in 12 equal monthly installments following May 29, 2025 until such time as the option is 100% vested, subject to Peter Harwin's continuous service with the Issuer at each vesting date. |
| F2 | Under Mr. Harwin's arrangement with Fairmount Funds Management LLC (the "Adviser"), Mr. Harwin holds the option for one or more investment vehicles managed by the Adviser (each, a "Fairmount Fund"). Mr. Harwin is obligated to turn over to the Adviser any net cash or stock received from the option for the benefit of such Fairmount Fund. Mr. Harwin therefore disclaims beneficial ownership of the option and underlying common stock, except to the extent of his pecuniary interest therein. |
| F3 | This option represents a right to purchase 25,000 shares of the Issuer's common stock, which will vest and become exercisable in 12 equal monthly installments following May 29, 2025 until such time as the option is 100% vested, subject to Tomas Kiselak's continuous service with the Issuer at each vesting date. |
| F4 | Under Mr. Kiselak's arrangement with Fairmount Funds Management LLC (the "Adviser"), Mr. Kiselak holds the option for one or more investment vehicles managed by the Adviser (each, a "Fairmount Fund"). Mr. Kiselak is obligated to turn over to the Adviser any net cash or stock received from the option for the benefit of such Fairmount Fund. Mr. Kiselak therefore disclaims beneficial ownership of the option and underlying common stock, except to the extent of his pecuniary interest therein. |
The Adviser and Fairmount Healthcare Fund II L.P. may each be deemed a director by deputization of Issuer by virtue of the fact that each of Peter Harwin and Tomas Kiselak serve on the board of directors of the Issuer and are also each a Managing Member of the Adviser.