Rebecca Taub - 09 Jan 2026 Form 4 Insider Report for MADRIGAL PHARMACEUTICALS, INC. (MDGL)

Role
Director
Signature
/s/ Mardi Dier, as Attorney-in-Fact
Issuer symbol
MDGL
Transactions as of
09 Jan 2026
Net transactions value
-$9,326,434
Form type
4
Filing time
13 Jan 2026, 16:34:08 UTC
Previous filing
12 Dec 2025
Next filing
20 Jan 2026
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Taub Rebecca Director C/O MADRIGAL PHARMACEUTICALS, INC., 200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN /s/ Mardi Dier, as Attorney-in-Fact 13 Jan 2026 0001423898

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction MDGL Common Stock Options Exercise $290,878 +18,410 +4% $15.80 473,999 09 Jan 2026 Direct
transaction MDGL Common Stock Sale $491,537 -960 -0.2% $512.02 473,039 09 Jan 2026 Direct F1, F2
transaction MDGL Common Stock Sale $492,595 -960 -0.2% $513.12 472,079 09 Jan 2026 Direct F1, F3
transaction MDGL Common Stock Sale $482,207 -937 -0.2% $514.63 471,142 09 Jan 2026 Direct F1, F4
transaction MDGL Common Stock Sale $813,968 -1,578 -0.33% $515.82 469,564 09 Jan 2026 Direct F1, F5
transaction MDGL Common Stock Sale $269,257 -521 -0.11% $516.81 469,043 09 Jan 2026 Direct F1, F6
transaction MDGL Common Stock Sale $1,058,468 -2,044 -0.44% $517.84 466,999 09 Jan 2026 Direct F1, F7
transaction MDGL Common Stock Sale $503,106 -970 -0.21% $518.67 466,029 09 Jan 2026 Direct F1, F8
transaction MDGL Common Stock Sale $280,220 -539 -0.12% $519.89 465,490 09 Jan 2026 Direct F1, F9
transaction MDGL Common Stock Sale $229,289 -440 -0.09% $521.11 465,050 09 Jan 2026 Direct F1, F10
transaction MDGL Common Stock Sale $306,909 -588 -0.13% $521.95 464,462 09 Jan 2026 Direct F1, F11
transaction MDGL Common Stock Sale $382,823 -732 -0.16% $522.98 463,730 09 Jan 2026 Direct F1, F12
transaction MDGL Common Stock Sale $699,623 -1,335 -0.29% $524.06 462,395 09 Jan 2026 Direct F1, F13
transaction MDGL Common Stock Sale $781,903 -1,489 -0.32% $525.12 460,906 09 Jan 2026 Direct F1, F14
transaction MDGL Common Stock Sale $480,281 -913 -0.2% $526.05 459,993 09 Jan 2026 Direct F1, F15
transaction MDGL Common Stock Sale $598,091 -1,135 -0.25% $526.95 458,858 09 Jan 2026 Direct F1, F16
transaction MDGL Common Stock Sale $245,593 -465 -0.1% $528.16 458,393 09 Jan 2026 Direct F1, F17
transaction MDGL Common Stock Sale $293,222 -554 -0.12% $529.28 457,839 09 Jan 2026 Direct F1, F18
transaction MDGL Common Stock Sale $135,796 -256 -0.06% $530.45 457,583 09 Jan 2026 Direct F1, F19
transaction MDGL Common Stock Sale $15,932 -30 -0.01% $531.05 457,553 09 Jan 2026 Direct F1
transaction MDGL Common Stock Sale $21,300 -40 -0.01% $532.50 457,513 09 Jan 2026 Direct F1
transaction MDGL Common Stock Sale $144,761 -271 -0.06% $534.18 457,242 09 Jan 2026 Direct F1, F20
transaction MDGL Common Stock Sale $47,609 -89 -0.02% $534.93 457,153 09 Jan 2026 Direct F1, F21
transaction MDGL Common Stock Sale $160,205 -299 -0.07% $535.80 456,854 09 Jan 2026 Direct F1, F22
transaction MDGL Common Stock Sale $206,700 -385 -0.08% $536.88 456,469 09 Jan 2026 Direct F1, F23
transaction MDGL Common Stock Sale $21,514 -40 -0.01% $537.84 456,429 09 Jan 2026 Direct F1
transaction MDGL Common Stock Sale $215,706 -400 -0.09% $539.26 456,029 09 Jan 2026 Direct F1, F24
transaction MDGL Common Stock Sale $21,610 -40 -0.01% $540.26 455,989 09 Jan 2026 Direct F1
transaction MDGL Common Stock Sale $217,088 -400 -0.09% $542.72 455,589 09 Jan 2026 Direct F1
holding MDGL Common Stock 655,540 09 Jan 2026 By SQN, LLC F25

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction MDGL Stock Option (Right to Buy) Options Exercise $0 -18,410 -99% $0.000000 240 09 Jan 2026 Common Stock 18,410 $15.80 Direct F26
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025.
F2 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $511.71 to $512.56, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote and the footnotes below.
F3 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $513.00 to $513.58, inclusive.
F4 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $514.32 to $515.25, inclusive.
F5 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $515.32 to $516.29, inclusive.
F6 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $516.32 to $517.26, inclusive.
F7 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $517.36 to $518.35, inclusive.
F8 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $518.39 to $519.29, inclusive.
F9 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $519.45 to $520.38, inclusive.
F10 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $520.46 to $521.45, inclusive.
F11 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $521.50 to $522.49, inclusive.
F12 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $522.51 to $523.47, inclusive.
F13 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $523.59 to $524.58, inclusive.
F14 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $524.59 to $525.56, inclusive.
F15 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $525.59 to $526.55, inclusive.
F16 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $526.63 to $527.58, inclusive.
F17 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $527.71 to $528.52, inclusive.
F18 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $528.72 to $529.69, inclusive.
F19 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $529.97 to $530.63, inclusive.
F20 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $533.60 to $534.57, inclusive.
F21 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $534.60 to $534.99, inclusive.
F22 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $535.62 to $536.32, inclusive.
F23 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $536.64 to $537.30, inclusive.
F24 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $539.00 to $539.44, inclusive.
F25 The Reporting Person and her spouse are each managing members of SQN, LLC. The Reporting Person disclaims beneficial ownership of these securities except to the extent of her pecuniary interest therein, if any, and the inclusion of these shares in this report shall not be deemed an admission of the beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose.
F26 The shares underlying this stock option are fully vested and exercisable.