| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Brumm Joshua T | Chief Executive Officer, Director | C/O CRESCENT BIOPHARMA, INC., 300 FIFTH AVENUE, WALTHAM | /s/ Barbara Bispham, as attorney-in-fact for Joshua T. Brumm | 2025-12-10 | 0001528826 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CBIO | Stock Option (Right to Buy) | Award | $0 | +346K | $0.00 | 346K | Dec 8, 2025 | Ordinary Shares | 346K | $13.17 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | This option represents a right to purchase shares of the Issuer's ordinary shares and vests in 48 approximately equal monthly installments that commenced on December 8, 2025. |