Carole Huntsman - 21 Nov 2025 Form 4 Insider Report for MADRIGAL PHARMACEUTICALS, INC. (MDGL)

Signature
/s/ Mardi Dier, as Attorney-in-Fact
Issuer symbol
MDGL
Transactions as of
21 Nov 2025
Net transactions value
-$1,082,986
Form type
4
Filing time
21 Nov 2025, 17:39:36 UTC
Previous filing
07 Mar 2025
Next filing
26 Jan 2026

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Huntsman Carole Chief Commercial Officer C/O MADRIGAL PHARMACEUTICALS, INC., 200 BARR HARBOR DRIVE, SUITE 200, WEST CONSHOHOCKEN /s/ Mardi Dier, as Attorney-in-Fact 21 Nov 2025 0002001571

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction MDGL Common Stock Sale $492,567 -894 -7.5% $550.97 11,096 21 Nov 2025 Direct F1
transaction MDGL Common Stock Sale $78,807 -144 -1.3% $547.27 10,952 21 Nov 2025 Direct F2, F3
transaction MDGL Common Stock Sale $65,845 -120 -1.1% $548.71 10,832 21 Nov 2025 Direct F2, F4
transaction MDGL Common Stock Sale $21,974 -40 -0.37% $549.34 10,792 21 Nov 2025 Direct F2, F5
transaction MDGL Common Stock Sale $110,477 -200 -1.9% $552.38 10,592 21 Nov 2025 Direct F2, F6
transaction MDGL Common Stock Sale $22,129 -40 -0.38% $553.23 10,552 21 Nov 2025 Direct F2, F7
transaction MDGL Common Stock Sale $66,725 -120 -1.1% $556.04 10,432 21 Nov 2025 Direct F2, F8
transaction MDGL Common Stock Sale $111,920 -200 -1.9% $559.60 10,232 21 Nov 2025 Direct F2, F9
transaction MDGL Common Stock Sale $44,850 -80 -0.78% $560.62 10,152 21 Nov 2025 Direct F2, F10
transaction MDGL Common Stock Sale $22,528 -40 -0.39% $563.21 10,112 21 Nov 2025 Direct F2
transaction MDGL Common Stock Sale $45,165 -80 -0.79% $564.56 10,032 21 Nov 2025 Direct F2, F11
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 The sale reported on this line represents the number of shares sold by the Issuer on behalf of the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. This sale was automatic and not at the discretion of the Reporting Person.
F2 These sales were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 5, 2024.
F3 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $547.12 to $547.42, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote and the footnotes below.
F4 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $548.25 to $548.94, inclusive.
F5 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $549.30 to $549.38, inclusive.
F6 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $551.96 to $552.81, inclusive.
F7 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $553.22 to $553.23, inclusive.
F8 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $555.74 to $556.19, inclusive.
F9 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $559.22 to $560.06, inclusive.
F10 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $560.24 to $561.00, inclusive.
F11 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $564.55 to $564.58, inclusive.