| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Niklason Laura E | President, CEO and Director, Director | 2525 EAST NORTH CAROLINA HIGHWAY 54, DURHAM | /s/ Laura E. Niklason by Dale A. Sander as Attorney-in-Fact | 17 Nov 2025 | 0001878075 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | HUMA | Stock Options (right to buy) | Award | $0 | +311,100 | $0.000000 | 311,100 | 16 Nov 2025 | Common Stock | 311,100 | $1.23 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | The first 1/3 of the option becomes exercisable on February 14, 2026, after which 1/3 of the option will become exercisable on November 16, 2026, and the remaining 1/3 of the option will become exercisable on November 16, 2027. |