Laura A. Williams - 21 Aug 2025 Form 4 Insider Report for ARDELYX, INC. (ARDX)

Role: Chief Patient Officer
Signature: /s/ Elizabeth Grammer, Attorney-in-Fact for Laura A. Williams
Issuer symbol: ARDX
Transactions as of: 21 Aug 2025
Net transactions value: -$37,138
Form type: 4
Filing time: 25 Aug 2025, 21:13:45 UTC
Previous filing: 22 May 2025
Next filing: 28 Aug 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Williams Laura A	Chief Patient Officer	C/O ARDELYX, INC., 400 FIFTH AVENUE, SUITE 210, WALTHAM	/s/ Elizabeth Grammer, Attorney-in-Fact for Laura A. Williams	25 Aug 2025	0001869194

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	ARDX	Common Stock	Sale	$37,138	-6,261	-1.6%	$5.93	396,322	21 Aug 2025	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Pursuant to an automatic sell-to-cover imposed by the terms of the initial grant of the restricted stock units ("RSUs") awards, the shares were sold upon the vesting of the RSUs solely to cover applicable withholding taxes.