Jeffrey D. Marrazzo - 04 Jun 2025 Form 4 Insider Report for Prime Medicine, Inc. (PRME)

Role: Director
Signature: /s/ Ryan Brown, attorney-in-fact
Issuer symbol: PRME
Transactions as of: 04 Jun 2025
Net transactions value: $0
Form type: 4
Filing time: 05 Jun 2025, 18:13:50 UTC
Previous filing: 19 May 2025
Next filing: 05 Aug 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Marrazzo Jeffrey D	Director	C/O PRIME MEDICINE, INC., 60 FIRST STREET, CAMBRIDGE	/s/ Ryan Brown, attorney-in-fact	05 Jun 2025	0001631262

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	PRME	Stock Option (right to buy)	Award	$0	+55,000		$0.000000	55,000	04 Jun 2025	Common Stock	55,000	$1.32	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The shares subject to this option shall vest in full upon the earlier of (i) June 4, 2026 or (ii) the date of the next annual meeting of stockholders, subject to the Reporting Person's continuous service to the Issuer through such vesting date.